Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6382757 | Aquatic Toxicology | 2012 | 11 Pages |
Abstract
⺠This is the first study of triclosan and methyl triclosan biotransformation in a fish species ⺠Methyl triclosan was very slowly O-demethylated in the channel catfish liver and intestine ⺠The demethylation was inhibited by DMSO, a solvent commonly used in toxicology studies ⺠Triclosan was rapidly conjugated by glucuronidation and sulfonation ⺠Our results suggest methyl triclosan, but not triclosan, will bioaccumulate in exposed catfish.
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Authors
Margaret O. James, Christopher J. Marth, Laura Rowland-Faux,