Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6382768 | Aquatic Toxicology | 2012 | 8 Pages |
Abstract
⺠Significant molecular and cellular effects were observed in digestive gland of mussels exposed in vivo to Cr(VI) in the ng/L range. ⺠Lysosomal biomarkers indicated the development of a stress syndrome at 10 and 50 ng/L Cr(VI). ⺠Changes in mRNA expressions were seen at 1 ng/L Cr(VI) by a oligonucleotide microarray and Real-Time PCR. ⺠Expression profiles of stress-related gene products provide early signatures forecasting changes at higher levels of the biological organization.
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Authors
Silvia Franzellitti, Aldo Viarengo, Enrico Dinelli, Elena Fabbri,