| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6382805 | Aquatic Toxicology | 2012 | 8 Pages |
Abstract
⺠We cloned a new c DNA of the CYP1C subfamily encoding CYP1C1 Nile tilapia liver after intraperitoneal injection with benzo-a-pyrene (BaP). ⺠The full-length cDNA was 2223 bp long and contained an open reading frame of 1581 bp. ⺠The phylogenetic tree shows tilapia CYP1C1 and scup CYP1C1 to be more closely related to each other. ⺠We measured benzo-a-pyrene (BaP) induction of CYP1C1 mRNA in different organs of tilapia. ⺠Real time RCR results revealed that there was a large increase in CYP1C1 mRNA in liver (43.1), intestine (5.1) and muscles (2.4).
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Authors
Abeer A.I. Hassanin, Yoshino Kaminishi, Aki Funahashi, Takao Itakura,