Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6578675 | Chemical Engineering Journal | 2018 | 46 Pages |
Abstract
In this study, crude glycerol was demonstrated as feedstock to use in the fed-batch fermentation of 1,3-propanediol production by Klebsiella pneumoniae ATCC 8724. To increase the yield and productivity of 1,3-propanediol, several factors for fed-batch fermentation were investigated, which included: initial substrate conditions, feeding strategy and fermentation conditions. Both performances of 1,3-propandiol and by-products were observed and studied for improved fed-batch fermentation. Increasing of initial working volume, continuous feeding, and culture pH switch strategy showed positive performance for this fed-batch process. The maximum 1,3-propandiol concentration, yield, and productivity were achieved 62.72â¯g/l, 0.73â¯mol/mol and 1.74â¯g/l/h, respectively. With the ignorable inhibitory effect, a large quantity of crude glycerol from industrial biodiesel process would be an attractive feedstock for value-added chemical, 1,3-propandiol, manufacture. The improvement of fed-batch fermentation could also be achieved by strategy optimization in further applications.
Related Topics
Physical Sciences and Engineering
Chemical Engineering
Chemical Engineering (General)
Authors
Xiaoguang Yang, Han Suk Choi, Ju Hun Lee, Soo Kwon Lee, Sung Ok Han, Chulhwan Park, Seung Wook Kim,