Article ID Journal Published Year Pages File Type
6866929 Neurocomputing 2012 5 Pages PDF
Abstract
The present study used trios of two familiar male mice of the same strain and an intruder of a different strain to evaluate the robustness of the protocol in encounters involving strains with different motor activity levels. The results validated the methods and showed subtle inter-strain differences in reactions to the presence of an intruder. The frequency and mean duration of the proximity episodes showed an inter-strain difference in social interactions with the intruder: B6 increased the duration of contacts without changing the frequency, whereas 129S2 increased the frequency of contacts but these were of a shorter duration. The results are discussed in relation to a possible effect of strain differences on anxiety levels or, more generally, the influence of genetic background on the social behaviour of mice.
Related Topics
Physical Sciences and Engineering Computer Science Artificial Intelligence
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