Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7454564 | Global Food Security | 2017 | 11 Pages |
Abstract
This paper reviews and compiles up-to-date literature on reported human intoxications following exposure to marine biotoxins through seafood consumption. The review includes a discussion about prevention of such outbreaks and surveillance programs to identify possible limitations and approaches for limiting the impact of HABs on human health. It is concluded that marine biotoxins represent a threat to human health as thousands of poisonings following consumption of seafood contaminated with marine biotoxins were reported in the 21st century, emphasizing the need for carrying on/developing surveillance programs to detect the presence of HABs, and for development, validation and implementation of sensitive high-throughput methods for detecting these biotoxins in seafood to protect consumers. Regarding the possible presence of unknown toxins and general lack of standards for many known toxins, in vitro effect-based bioassays may play an important role in the monitoring for biotoxins.
Keywords
PP1AMPANMDAN-methyl-d-aspartatePTXCTXVGCCVGSCMTXMBAAZATTXSTXAzaspiracidPectenotoxinDTXDinophysistoxinAZPYTXPbTxAzaspiracid poisoningadenosine-5-triphosphateEFSANSPHPLC-UVPSPASPAOACCFPDSPBrevetoxinATPMouse BioassayEuropean Food Safety Authorityα-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acidOkadaic acidAssociation of Analytical CommunitiesFood safetyMarine biotoxinstetrodotoxinELISAEnzyme-linked immunosorbent assayDomoic acidFood and Agriculture OrganizationHuman healthSaxitoxinCyclic imineOutbreaksFAOMaitotoxinDiarrhetic Shellfish Poisoningamnesic shellfish poisoningCiguatera fish poisoningParalytic shellfish poisoningmouse unitPalytoxinvoltage-gated sodium channelsvoltage-gated calcium channelsHigh performance liquid chromatography with ultraviolet detectionCiguatoxinYessotoxin
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Authors
Jonathan Nicolas, Ron L.A.P. Hoogenboom, Peter J.M. Hendriksen, Marcia Bodero, Toine F.H. Bovee, Ivonne M.C.M. Rietjens, Arjen Gerssen,