Article ID Journal Published Year Pages File Type
7749872 Inorganic Chemistry Communications 2012 4 Pages PDF
Abstract
► We report synthesis of ATRA-hydrazonates and their copper complexes. ► Compounds tested against hormone-dependent and independent breast, prostate cancers. ► Compounds inhibited growth of cancer cells, expressing RARα receptors, ► Compounds represent novel anticancer agents targeting nuclear retinoid receptors.
Keywords
Related Topics
Physical Sciences and Engineering Chemistry Inorganic Chemistry
Preview
ATRA-hydrazonate derivatives and their copper complexes against hormone-dependent (MCF-7), hormone-independent (MDA-MB-231and BT-20) breast cancer and androgen-independent (PC3) prostate cancer cell lines
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