| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7779698 | Bioorganic & Medicinal Chemistry Letters | 2018 | 5 Pages |
Abstract
A novel series of o-phenylenediamine-based inhibitors of indoleamine 2,3-dioxygenase (IDO) has been identified. Compound 19 demonstrated significant potency in the HeLa human cervical cancer IDO1 assay.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
David K. Williams, Jay A. Markwalder, Aaron J. Balog, Bin Chen, Libing Chen, Jennifer Donnell, Lauren Haque, Amy C. Hart, Sunil K. Mandal, Andrew Nation, Weifang Shan, Gregory D. Vite, Kelly Covello, John T. Hunt, Maria N. Jure-Kunkel, Steven P. Seitz,