Discovery of N-substituted 7-azaindoles as Pan-PIM kinase inhibitors - Lead series identification

Article ID	Journal	Published Year	Pages	File Type
7780821	Bioorganic & Medicinal Chemistry Letters	2017	6 Pages	PDF

Keywords

AML PK/PD X-ray crystallography Cancer Hit-to-lead Small molecule inhibitor

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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Discovery of N-substituted 7-azaindoles as Pan-PIM kinase inhibitors - Lead series identification - Part II

Authors

Claude Barberis, Neil Moorcroft, James Pribish, Elina Tserlin, Alexandre Gross, Mark Czekaj, Matthieu Barrague, Paul Erdman, Tahir Majid, Joseph Batchelor, Mikhail Levit, Andrew Hebert, Liduo Shen, Sandra Moreno-Mazza, Anlai Wang,