| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8262324 | Experimental Gerontology | 2018 | 21 Pages |
Abstract
The odds ratio of AD was 1.09 (95% confidence interval, 0.98 to 1.22; p â¯=â¯Â 0.10) per one standard deviation genetically elevated GGT based on all 26 SNPs. The results were similar in both MR-Egger and weighted median MR methods. Overall, our findings cannot confirm a strong causal effect of GGT on AD risk. Further MR investigations using individual-level data are warranted to confirm or rule out causality.
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Authors
Setor K. Kunutsor, Jari A. Laukkanen, Stephen Burgess,