Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8298833 | Biochimica et Biophysica Acta (BBA) - Bioenergetics | 2011 | 6 Pages |
Abstract
âºThe permeability transition pore (PTP) is an inner membrane mitochondrial channel. âºThe rat-selective toxicant norbormide (NRB) is species-selective for PTP opening. âºThe PTP-inducing effect is lost in mitoplasts (devoid of the outer membrane). âºNRB transport depends on the outer membrane protein TSPO. âºWe have tentatively identified the TSPO residues responsible for transport of NRB.
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Authors
Alessandra Zulian, Justina Å ileikytÄ, Valeria Petronilli, Sergio Bova, Federica Dabbeni-Sala, Gabriella Cargnelli, David Rennison, Margaret A. Brimble, Brian Hopkins, Paolo Bernardi, Fernanda Ricchelli,