Article ID Journal Published Year Pages File Type
8349534 Pharmacological Reports 2018 11 Pages PDF
Abstract
Our data suggest that nickel released from orthodontic appliances activate tryptophan metabolism in oral cavity via the kynurenine pathway. The metal directly or through kynurenines enhancement activates oxidative stress and then via the caspase pathway induce apoptosis of buccal epithelial cells.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
An important pathway of apoptotic effect of nickel early released from orthodontic appliances - Preliminary data
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