| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8349608 | Pharmacological Reports | 2018 | 34 Pages |
Abstract
Blockade of 5-HT2A and 7 receptors each alone could be a future reliable therapeutic approach in liver fibrosis through a reduction in oxidative stress/TGF-β1-induced HSCs activation pathway.
Keywords
GSHMDAPINPSB-269970KetanserinCCl4ALTECMCAT5-HTTGF-β1ROSASTAspartate aminotransferaseAlanine aminotransferaseTransforming growth factor-beta1Enzyme-linked immunosorbent assayELISASODSerotoninHepatic stellate cellsSuperoxide dismutaseLiver fibrosisExtracellular matrixmalondialdehydeCatalasereduced glutathioneCarbon tetrachlorideReactive oxygen species
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Authors
Marwa Ahmed Amin Atallah, Samah M. Elaidy, Mona K. Tawfik,