Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8349676 | Pharmacological Reports | 2018 | 19 Pages |
Abstract
In this study, we clearly demonstrated that KNT-127 administration induces neither convulsive effects nor seizure spikes in mice. We propose that KNT-127 should be considered a candidate compound for the development of improved DOP-based psychotropic drug that lack the convulsive properties.
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Authors
Akiyoshi Saitoh, Hiromu Tominaga, Yasuhiro Ogawa, Yoko Irukayama-Tomobe, Mitsuhiko Yamada, Masashi Yanagisawa, Hiroshi Nagase,