| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8349809 | Pharmacological Reports | 2017 | 33 Pages |
Abstract
Our findings suggest that honokiol exhibits a modulatory role in adipocytes via induction of browning and apoptosis in white adipocytes, promotion of catabolic lipid metabolism, as well as activation and inhibition of apoptosis in HIB1B brown adipocytes, thereby exhibiting therapeutic potential against obesity.
Keywords
AMPKHSLFGF21Fat browningCITED1PGC-1αPRDM16/Prdm16PPARBATACOERKBcl-2PR domain-containing 16/encoding geneCPT3T3-L1 adipocytesAMP-activated protein kinaseWhite adipose tissuebrown adipose tissueBaxApoptosisAnti-obesityB-cell lymphoma 2hormone-sensitive lipaseHonokiolBcl-2-associated X proteinperilipinWATCarnitine palmitoyltransferasePLINCideaExtracellular signal–regulated kinaseperoxisome proliferator-activated receptor
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Authors
Jameel Lone, Jong Won Yun,