| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8349814 | Pharmacological Reports | 2017 | 24 Pages |
Abstract
In conclusion, RVD-hemopressin(α) administration has an anorectic effect, possibly related to inhibition of POMC and NE levels in the hypothalamus. Despite decreased food intake, body weight is not affected by RVD-hemopressin(α) treatment, possibly due to inhibition of UCP-1 gene expression in BAT.
Keywords
5-HTUCP-1pro-opiomelanocortinFAAHCARTReal-time RT PCRBATPOMCAgRPNPYTFA4-dimethylaminopyridineACNDMAPDCMDMFCRHnuclear magnetic resonanceDMSOESI–MSN,N-diisopropylethylamineAcetonitrileTrifluoroacetic acidFatty acid amide hydrolasebrown adipose tissueNMRFeedingUncoupling protein-1DopaminedimethylformamideDichloromethaneDimethyl sulfoxideSerotoninelectrospray ionisation mass spectrometryArcDIPEAnorepinephrineHATUarcuate nucleuscorticotrophin releasing hormonereal-time reverse transcription polymerase chain reactionproopiomelanocortinCocaine and amphetamine-regulated transcriptNeuropeptide Y
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Authors
Claudio Ferrante, Lucia Recinella, Sheila Leone, Annalisa Chiavaroli, Chiara Di Nisio, Sara Martinotti, Adriano Mollica, Giorgia Macedonio, Azzurra Stefanucci, Szabolcs Dvorácskó, Csaba Tömböly, Luciano De Petrocellis, Michele Vacca, Luigi Brunetti,