| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8349821 | Pharmacological Reports | 2017 | 17 Pages |
Abstract
Our results showed a superior anticancer activity of curcumin-loaded lipid-core nanocapsules compared to curcumin-loaded nanoemulsion and curcumin dissolved in DMSO in long exposition time assay, wihch is not observed in short exposition time assays like MTT. When a poorly water-soluble drug is under investigation, the nanoemulsion prepared with the same compounds of the nanocapsules, except the polymer, could be a better control than DMSO-solution of drug.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Eduarda Schultze, Karine Coradini, Paula dos Santos Chaves, Liziane Pereira da Silva, Julieti Buss, Silvia S. Guterres, Tiago Collares, Ruy Carlos Ruver Beck, Adriana R. Pohlmann, Fabiana Kömmling Seixas,