Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8361833 | Seminars in Cancer Biology | 2017 | 39 Pages |
Abstract
In this review, we describe the current knowledge of the etiopathogenic events that may lead to oncocytic transformation and discuss their contribution for tumor progression and mitochondrial accumulation.
Keywords
SDHBHCTPRCDCATFAMMAXRCCccRCCHIF1αtRNANRF-1GRIM-19SGOFLCNTK2Succinate dehydrogenase subunit BDAP3rRNAERRαSTAT3nDNAMMPPCCOXPHOSTCOOPAMitochondrial DNANuclear DNARibosomal RNAROSAutophagytransfer RNARenal oncocytomaDichloroacetatemtDNAelectron transport chainClear cell renal cell carcinomahypoxia inducible factor 1 alphaNuclear respiratory factor 1mitochondrial transcription factor AOxidative phosphorylationsignal transducer and activator of transcription 3MitophagyPROETcMitochondrial membrane potentialAGORenal cell carcinomaReactive oxygen speciesEstrogen-related receptor alpha
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Authors
Marcelo Correia, Pedro Pinheiro, Rui Batista, Paula Soares, Manuel Sobrinho-Simões, Valdemar Máximo,