Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8393007 | Reproductive Biology | 2018 | 4 Pages |
Abstract
The influence of exposure to overfeeding-induced maternal obesity around the time of conception on early embryogenesis was examined in the day 14 ovine conceptus. The relative abundance of FGFR2 and DNMT1 was influenced by maternal obesity status and conceptus sex, and the abundance of PPARG and PTGS2 transcripts was greater in male conceptuses regardless of the obesity status of the ewe. These observations demonstrated that short-term exposure to maternal obesity impacts early conceptus transcript patterning.
Keywords
trophectodermcaudal type homeobox 2hand1IFNTDOHaDGATA4PPARGCIDRAscl2FGFR2CDX2Ptgs2FGFqRT-PCRapoA1Apolipoprotein A1corpora luteaPrimitive endodermInterferon-tauPregnancyPlacentaEmbryostandard error of the meanfibroblast growth factorpreSEMquantitative reverse transcription polymerase chain reactionPeroxisome proliferator-activated receptor gammaSheep
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Authors
Sarah R. McCoski, Rebecca K. Poole, McCauley T. Vailes, Alan D. Ealy,