| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8424843 | Stem Cell Research | 2018 | 9 Pages |
Abstract
This is the first use of Chinese herb derived-natural products to promote neurogenesis of ESCs, including the generation of serotonergic neurons, and the first attempt to identify the active compound in Hypericum longistylum responsible for its beneficial effects on depressive diseases.
Keywords
5-HT5-hydroxytryptaminehESCsECDFGF4ESCsTLCFGF8TCAmESCsTDDFTbFGFMPLCNSCODSLIFOctadecylsilylFACSnuclear magnetic resonanceBDNFNPCstrichloroacetic acidChemical modificationDepressionNMRCell differentiationNeural differentiationembryoid bodyShhChinese medicinefluorescence-activated cell sortingElectronic circular dichroismRetinoic acidSERTserotonin transporterhuman embryonic stem cellsMouse embryonic stem cellsNeural stem cellNeural precursor cellsEmbryonic stem cellssonic hedgehogmass spectrometerleukemia inhibitory factorbasic fibroblast growth factorBrain-derived neurotrophic factorfibroblast growth factor-4Time-dependent density functional theorySerotonergic neuronthin layer chromatographyMedium pressure liquid chromatographyhigh-performance liquid chromatographyHPLC
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biotechnology
Authors
Haisong Wang, Wenhao Zhang, Qian Gao, Xiangrong Cao, Yanni Li, Xu Li, Zheying Min, Yang Yu, Yuanqiang Guo, Ling Shuai,