Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8424938 | Stem Cell Research | 2018 | 4 Pages |
Abstract
Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome and its prevalence increases continuously. Here, we reprogrammed fibroblasts of a high grade NAFLD patient with homozygous wildtype PNPLA3 genotype. The induced pluripotent stem cells (iPSCs) were characterized by immunocytochemistry, flow cytometry, embryoid body formation, pluritest, DNA-fingerprinting and karyotype analysis.
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Authors
Nina Graffmann, Martina Bohndorf, Audrey Ncube, Marie-Ann Kawala, Wasco Wruck, Karl Kashofer, Kurt Zatloukal, James Adjaye,