Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8425241 | Stem Cell Research | 2018 | 9 Pages |
Abstract
Retinoblastoma (RB) is a pediatric intraocular tumor caused by mutations in retinoblastoma (RB1) gene. We have generated induced pluripotent stem cell line VRFi001-A from a bilateral retinoblastoma patient with heterozygous RB1 gene deletion. The iPSC line VRFi001-A retained the mutation and expressed pluripotency markers, had a normal karyotype and was capable of trilineage differentiation.
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Authors
Ambily Vincent, Vikas Khetan, Pukhraj Rishi, Ganesan Suganeswari, Subramanian Krishnakumar, Uma Maheswari Krishnan, Sowmya Parameswaran,