Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8425401 | Stem Cell Research | 2018 | 15 Pages |
Abstract
A DAND5-control human iPSC line was generated from the urinary cells of a phenotypically normal donor. Exfoliated renal epithelial (RE) cells were collected and reprogrammed into iPSCs using Sendai virus reprogramming system. The pluripotency, in vitro differentiation potential, karyotype stability, and the transgene-free status of generated iPSC line were analyzed and confirmed. This cell line can be exploited as a control iPSC line to better understand the mechanisms involved in DAND5-associated cardiac disease.
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Authors
Selin Pars, Fernando Cristo, José M. Inácio, Graça Rosas, Isabel Marques Carreira, Joana Barbosa Melo, PatrÃcia Mendes, Duarte Saraiva Martins, LuÃs Pereira de Almeida, José Maio, Rui Anjos, José A. Belo,