Article ID Journal Published Year Pages File Type
8425401 Stem Cell Research 2018 15 Pages PDF
Abstract
A DAND5-control human iPSC line was generated from the urinary cells of a phenotypically normal donor. Exfoliated renal epithelial (RE) cells were collected and reprogrammed into iPSCs using Sendai virus reprogramming system. The pluripotency, in vitro differentiation potential, karyotype stability, and the transgene-free status of generated iPSC line were analyzed and confirmed. This cell line can be exploited as a control iPSC line to better understand the mechanisms involved in DAND5-associated cardiac disease.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biotechnology
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