Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8425760 | Stem Cell Research | 2017 | 38 Pages |
Abstract
We analyzed whether the inactivation of key translation initiation factors was involved in this observed major repression of translation. We showed that there was an increase in the hypo phosphorylated forms of 4E-BP1, a negative regulator of translation, during early adipogenesis. Our results showed that extensive translational regulation occurred during the early stage of the adipogenic differentiation of hASCs.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biotechnology
Authors
Bruna H. Marcon, FabÃola B. Holetz, Guillermo Eastman, Ana Carolina Origa-Alves, Mariana Andrea Amorós, Alessandra Melo de Aguiar, Carmen K. Rebelatto, Paulo R.S. Brofman, Jose Sotelo-Silveira, Bruno Dallagiovanna,