Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8493703 | Aquaculture | 2016 | 7 Pages |
Abstract
3. In this study, we identified several gene variations of VHSV NV protein from 13 VHSV specimens of severe VHS-showing olive flounders in Korea. The gene variations are associated with amino acid changes of VHSV NV proteins. The amino acid variants of NV protein show the inhibitory activity of fish cellular energy (ATP) generation. The cellular energy deprivation might give a big impact on fish health and mortality. The DNA mutation on specific amino acid changes is possibly applied to develop the PCR diagnosis system for early detection of high pathogenic VHSV appearance. The early pathogenic gene diagnosis of VHSV gives more efficient prevention of epidemics.
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Authors
Jee Youn Hwang, Mi Young Cho, Seong Don Hwang, Myoung Ae Park, Hyun Kook Cho, So Young Kim, Mi So Sung, Dong Uk Kim, JaeHun Cheong,