Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8493896 | Aquaculture | 2016 | 5 Pages |
Abstract
In this paper, we generated auxotrophic Vibrio anguillarum mutants by knockout of alanine racemase genes, and evaluated their potential as a prophylactic vaccine in olive flounder. The results of the vaccine experiment showed that the survival rate and serum agglutination titer of fish immunized with 1Â ÃÂ 105Â CFU/fish of Îalr1Îalr2 V. anguillarum were significantly higher than fish immunized with 1Â ÃÂ 105Â CFU/fish of FKC V. anguillarum, suggesting that Îalr1Îalr2 V. anguillarum can elicit protective immune responses more efficiently than FKC V. anguillarum.
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Aquatic Science
Authors
Seung Hyuk Choi, Min Sun Kim, Ki Hong Kim,