| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8500423 | Journal of Comparative Pathology | 2018 | 5 Pages |
Abstract
Renal capillary rarefaction is a crucial event that leads to tubulointerstitial damage during the progression of chronic kidney disease (CKD). In the present study, changes in CD34-positive renal capillaries were investigated in dogs and cats with CKD. A significant decrease in CD34-positive capillaries was observed in canine diseased kidneys, even at the early stage of disease. In cats, CD34-positive capillaries were well preserved in the diseased kidneys, with no link to the severity of CKD. Renal capillary rarefaction might be a trigger event that leads to the progression of CKD in dogs, rather than in cats.
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Authors
R. Nakamura, A. Yabuki, O. Ichii, H. Mizukawa, N. Yokoyama, O. Yamato,