Conservation of coding and untranslated regions of heat shock protein Beta-1 (HSPB1) gene and its expression pattern in heat stressed peripheral blood mononuclear cells of Indian native cattle (Bos indicus) and riverine buffaloes (Bubalus bubalis)

Article ID	Journal	Published Year	Pages	File Type
8634886	Agri Gene	2018	9 Pages	PDF

Abstract

- HSPBI cDNA of Indian cattle characterized and compared with riverine buffaloes.
- Coding and UTRs of HSPB1 gene sequenced in 181 animals of 12 native cattle breeds.
- HSPB1 gene highly conserved across different cattle types and buffaloes.
- Expression analysis confirmed heat responsive nature of HSPB1 gene.
- Expression data of HSPB1 indicated lower tolerance to heat stress for buffalo's PBMCs.

Keywords

sHSPs PBMCs EGR-1 ACD DEC NMC HFC b2m Heat shock protein beta-1 HSPB1 DAC RKC GIC Heat treated NF-1 MUB Ribosomal protein S15 GATA-binding factor 1 Reb1 CTR ORF mGC THC SAC NF-kB HSD RAC LAC Hsp TRT Sp1 Beta-2-microglobulin peripheral blood mononuclear cells nuclear factor 1 nuclear factor kappa-light-chain-enhancer of activated B cells open reading frame UTR یا untranslated regions untranslated region Heat shock protein early growth response protein 1 Small heat shock proteins Single nucleotide polymorphism SNP Control GATA-1