| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8646656 | Infection, Genetics and Evolution | 2018 | 4 Pages |
Abstract
Burkholderia (B.) mallei is the causative agent of glanders. A previous work conducted on single-nucleotide polymorphisms (SNP) extracted from the whole genome sequences of 45 B. mallei isolates identified 3 lineages for this species. In this study, we designed a high-resolution melting (HRM) method for the screening of 15 phylogenetically informative SNPs within the genome of B. mallei that subtype the species into 3 lineages and 12 branches/sub-branches/groups. The present results demonstrate that SNP-based genotyping represent an interesting approach for the molecular epidemiology analysis of B. mallei.
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Authors
Girault G., Wattiau P., Saqib M., Martin B., Vorimore F., Singha H., Engelsma M., Roest H.J., Spicic S., Grunow R., Vicari N., De Keersmaecker S.C.J., Roosens N.H.C., Fabbi M., Tripathi B.N., Zientara S., Madani N., Laroucau K.,