An epigenetic basis for an omnigenic model of psychiatric disorders

- Recently, the omnigenic model for the inheritance of complex traits was proposed.
- There is increasing evidence that there are abnormalities of epigenetic mechanisms of gene expression underlying psychiatric disorders.
- This article invokes abnormalities of epigenetic mechanisms of gene expression to propose an omnigenic model for the inheritance of schizophrenia, bipolar disorder, and major depressive disorder.