Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8877052 | Mathematical Biosciences | 2018 | 27 Pages |
Abstract
In this work, we model osteoclast-osteoblast population dynamics with random environmental fluctuations in order to understand the random variations of the bone remodeling process in real life. For this purpose, we construct a stochastic differential model for the interactions between the osteoclast and osteoblast cell populations using the parameter perturbation technique. We prove the existence of a globally attractive positive unique solution for the stochastically perturbed system. Also, the stochastic boundedness of the solution is demonstrated using its p-th order moments for pâ¯â¥â¯1. Finally, we show that the introduction of noise in the deterministic model provides a fluctuating periodic solution. Numerical evidence supports our theoretical results and a discussion of the results is carried out.
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Authors
S. Jerez, S. DÃaz-Infante, B. Chen,