Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8878424 | Current Opinion in Insect Science | 2018 | 16 Pages |
Abstract
Mosquito specific viruses such as densonucleosis viruses ('densoviruses') have long been suggested as alternative mosquito control agents in the face of increasing insecticide resistance. Densoviruses are very species-specific and have been found to infect many important mosquito species. While some strains are highly pathogenic, other strains are more benign. Densoviruses have been proposed as a way to reduce mosquito populations through pathogenic interactions, but genetic strategies such as viral paratrangenesis offer new approaches. As small single-stranded DNA viruses, densoviruses can be easily genetically modified for the expression of genes or non-coding RNAs. A growing literature and variety of techniques have shown the potential for the use of densoviruses in the control of mosquitoes or mosquito-borne pathogens as well as the usefulness of densoviruses as molecular tools for understanding mosquito biology.
Related Topics
Life Sciences
Agricultural and Biological Sciences
Agronomy and Crop Science
Authors
Rebecca M Johnson, Jason L Rasgon,