Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8882284 | South African Journal of Botany | 2018 | 10 Pages |
Abstract
Our results revealed the high amount of phenolic compounds in both extracts; especially they were rich in condensed tannins. Ellagic acid and catechin were tentatively identified in AVA and AVR, respectively. Full biocompatibility as well as remarkable bioactivity were observed for both extracts in all employed assays, so our further investigations will be focused on the identification of active constituents in A. vulgaris and the molecular mechanisms of their action.
Keywords
PGH2NSAIDSNF-κBAVADEXiNOSCOX-1COX-2ROSAVRinterleukintumour necrosis factor αNon-steroidal anti-inflammatory drugsDexamethasoneBiocompatibilityinducible nitric oxide synthasecyclooxygenase-1Cyclooxygenase-2TNF-αAntioxidant activityAnti-inflammatory activityAntimicrobial activityProstaglandin H2Reactive oxygen species
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Authors
T. Boroja, V. MihailoviÄ, J. KataniÄ, S.-P. Pan, S. Nikles, P. Imbimbo, D.M. Monti, N. StankoviÄ, M.S. StankoviÄ, R. Bauer,