| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8919896 | Veterinary Anaesthesia and Analgesia | 2017 | 11 Pages |
Abstract
This study confirms that alfaxalone solubilised in 2-hydroxypropyl-β-cyclodextrin provides excellent total intravenous anaesthesia in rats. Sex-based differences in pharmacokinetics and pharmacodynamics were demonstrated and must be considered when designing biomedical research models using alfaxalone.
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Authors
Kate L. White, Stuart Paine, John Harris,