Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8980752 | Journal of Comparative Pathology | 2005 | 5 Pages |
Abstract
Ocular squamous cell carcinoma (OSCC) is a well-characterized tumour occurring spontaneously in cattle and other mammalian species but not previously reported in the goat. This report describes the histological features of well-differentiated OSCCs in twin goats. Biomolecular investigations led to the identification of Papillomavirus-related DNA sequences within the neoplastic ocular parenchyma of both animals, but immunohistochemical and ultrastructural studies failed to demonstrate viral particles. A putative role of Papillomavirus in the aetiology of OSCC is discussed, together with other possible causative factors.
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Authors
M. Marà , G. Di Guardo, A. Venuti, G. Marruchella, C. Palmieri, M. De Rugeriis, L. Petrizzi, P. Simeone, C. Rizzo, L. Della Salda,