| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9252757 | Hepatology Research | 2005 | 5 Pages |
Abstract
Both glucose and free fatty acids acutely stimulate insulin secretion but chronic exposure to high levels of either nutrient leads to impairment of beta cell function. The combination of insulin resistance and beta cell failure leads to diabetes. Nutrient toxicity is thus the driving cause of the diabetes epidemic that is being recorded around the world.
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Authors
Joseph Proietto,