| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 9252803 | Hepatology Research | 2005 | 6 Pages |
Abstract
The prevalence of PBC is strikingly increased in family members (frequency of 5.9%). Sera from PBC patients of the same family showed the same AMA reactivity profile, suggesting that development of AMA may be greatly influenced by certain underlying genetic factors. Large-scale genomic studies of familial PBC will be critical to identify mechanisms of disease susceptibility.
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Authors
Yoshizumi Hayase, Shinji Iwasaki, Naoaki Akisawa, Toshiji Saibara, Yoshiko Kadokawa, Katsuhisa Omagari, Takashi Maeda, Saburo Onishi,