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A new anti-obesity drug treatment: First clinical evidence that, antagonising glutamate-gated Ca2+ ion channels with memantine normalises binge-eating disorders

Article ID Journal Published Year Pages File Type
9549083 Economics & Human Biology 2005 9 Pages PDF
Abstract
We suggest to treat human obesity by protecting the hypothalamic signalling cascade of leptin action with low to moderate affinity, non-competitive NMDA-R antagonists that selectively block the GLU-gated Ca2+ ion channels.
Keywords
NMDA receptorbinge-eating disorderObesityarcuate nucleusglutamate
Related Topics
Life Sciences Agricultural and Biological Sciences Agricultural and Biological Sciences (General)
Preview
A new anti-obesity drug treatment: First clinical evidence that, antagonising glutamate-gated Ca2+ ion channels with memantine normalises binge-eating disorders
Authors
M. Hermanussen, J.A.F. Tresguerres,
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Journal
Economics & Human Biology
Journal: Economics & Human Biology
Related Categories
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binge-eating disorder
Obesity
arcuate nucleus
glutamate
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