Spike-timing dependent plasticity as a mechanism for ocular dominance shift

Spike-timing dependent plasticity (STDP) has been implicated in visual cortex modification. We created a model of ocular dominance (OD) shift based on STDP rules and compared it to experimental results. Although STDP proved to be a powerful mechanism for OD shift in our model, we found that it was unable to account for more subtle effects of monocular deprivation.