Statins meditate anti-atherosclerotic action in smooth muscle cells by peroxisome proliferator-activated receptor-γ activation Fulltext Access 8 Pages 2015
Different conformational dynamics of β-arrestin1 and β-arrestin2 analyzed by hydrogen/deuterium exchange mass spectrometry Fulltext Access 8 Pages 2015
The C-terminal domains of two homologous Oleaceae β-1,3-glucanases recognise carbohydrates differently: Laminarin binding by NMR Fulltext Access 9 Pages 2015
HemQ: An iron-coproporphyrin oxidative decarboxylase for protoheme synthesis in Firmicutes and Actinobacteria Fulltext Access 9 Pages 2015
Manganese ions induce H2O2 generation at the ubiquinone binding site of mitochondrial complex II Fulltext Access 9 Pages 2015
Loss of L-FABP, SCP-2/SCP-x, or both induces hepatic lipid accumulation in female mice Fulltext Access 9 Pages 2015
Properties of ultrathin cholesterol and phospholipid layers surrounding silicon-carbide nanotube: MD simulations Fulltext Access 9 Pages 2015
New insights in the catalytic mechanism of tyrosine ammonia-lyase given by QM/MM and QM cluster models Fulltext Access 9 Pages 2015
Triazole-linked phenyl derivatives: Redox mechanisms and in situ electrochemical evaluation of interaction with dsDNA Fulltext Access 9 Pages 2015
Biophysical processes affecting DOM dynamics at the Arno river mouth (Tyrrhenian Sea) Fulltext Access 9 Pages 2015
Cy3 and Cy5 dyes attached to oligonucleotide terminus stabilize DNA duplexes: Predictive thermodynamic model Fulltext Access 9 Pages 2015
The potency-insolubility conundrum in pharmaceuticals: Mechanism and solution for hepatitis C protease inhibitors Fulltext Access 9 Pages 2015
Pathogenic mutations causing glucose transport defects in GLUT1 transporter: The role of intermolecular forces in protein structure-function Fulltext Access 9 Pages 2015
Endurance training prevents TWEAK but not myostatin-mediated cardiac remodelling in cancer cachexia Fulltext Access 9 Pages 2015
Targeting acidity in diseased tissues: Mechanism and applications of the membrane-inserting peptide, pHLIP Fulltext Access 9 Pages 2015
Effects of osmolytes on protein-solvent interactions in crowded environment: Analyzing the effect of TMAO on proteins in crowded solutions Fulltext Access 9 Pages 2015
N-myristoylated ubiquitin ligase Cbl-b inhibitor prevents on glucocorticoid-induced atrophy in mouse skeletal muscle Fulltext Access 9 Pages 2015
Tellurite-mediated damage to the Escherichia coli NDH-dehydrogenases and terminal oxidases in aerobic conditions Fulltext Access 9 Pages 2015
PI3K/AKT and Mdm2 activation are associated with inhibitory effect of cAMP increasing agents on DNA damage-induced cell death in human pre-B NALM-6 cells Fulltext Access 9 Pages 2015
Regulation of myofibroblast differentiation by miR-424 during epithelial-to-mesenchymal transition Fulltext Access 9 Pages 2015
The busulfan metabolite EdAG irreversibly glutathionylates glutaredoxins Fulltext Access 9 Pages 2015
Expression and characterization of manganese lipoxygenase of the rice blast fungus reveals prominent sequential lipoxygenation of α-linolenic acid Fulltext Access 9 Pages 2015
Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM Fulltext Access 9 Pages 2015
Quantifying errors in flow measurement using phase contrast magnetic resonance imaging: comparison of several boundary detection methods Fulltext Access 9 Pages 2015
A new technique with high reproducibility to estimate renal oxygenation using BOLD-MRI in chronic kidney disease Fulltext Access 9 Pages 2015
Towards the identification of multi-parametric quantitative MRI biomarkers in lupus nephritis Fulltext Access 9 Pages 2015
Alpha B- and βA3-crystallins containing d-Aspartic acids exist in a monomeric state Fulltext Access 9 Pages 2015
The role of active site tyrosine 58 in Citrobacter freundii methionine γ-lyase Fulltext Access 9 Pages 2015
Characterization of recombinant biosynthetic precursors of the cysteine tryptophylquinone cofactors of l-lysine-epsilon-oxidase and glycine oxidase from Marinomonas mediterranea Fulltext Access 9 Pages 2015
Structures and binding studies of the complexes of phospholipase A2 with five inhibitors Fulltext Access 9 Pages 2015
Stanniocalcin-2 (STC2): A potential lung cancer biomarker promotes lung cancer metastasis and progression Fulltext Access 9 Pages 2015
New challenges in pseudopodial proteomics by a laser-assisted cell etching technique Fulltext Access 9 Pages 2015
Dandelion PPO-1/PPO-2 domain-swaps: The C-terminal domain modulates the pH optimum and the linker affects SDS-mediated activation and stability Fulltext Access 9 Pages 2015
Calcium binding to gatekeeper residues flanking aggregation-prone segments underlies non-fibrillar amyloid traits in superoxide dismutase 1 (SOD1) Fulltext Access 9 Pages 2015
Exploring human 40S ribosomal proteins binding to the 18S rRNA fragment containing major 3â²-terminal domain Fulltext Access 9 Pages 2015
The effect of TGF-beta-induced epithelial–mesenchymal transition on the expression of intracellular calcium-handling proteins in T47D and MCF-7 human breast cancer cells Fulltext Access 9 Pages 2015
The intrinsically disordered protein LEA7 from Arabidopsis thaliana protects the isolated enzyme lactate dehydrogenase and enzymes in a soluble leaf proteome during freezing and drying Fulltext Access 9 Pages 2015
In silico analysis of family GH77 with focus on amylomaltases from borreliae and disproportionating enzymes DPE2 from plants and bacteria Fulltext Access 9 Pages 2015
Cardiac transcription factor Nkx2.5 interacts with p53 and modulates its activity Fulltext Access 9 Pages 2015
Analysis of genetic polymorphism and biochemical characterization of a functionally decreased variant in prostacyclin synthase gene (CYP8A1) in humans Fulltext Access 9 Pages 2015
Store-operated calcium entry contributes to abnormal Ca2+ signalling in dystrophic mdx mouse myoblasts Fulltext Access 9 Pages 2015
Stark absorption spectroscopy on the carotenoids bound to B800-820 and B800-850 type LH2 complexes from a purple photosynthetic bacterium, Phaeospirillum molischianum strain DSM120 Fulltext Access 9 Pages 2015
A chain extension method for apocarotenoids; lycopene and lycophyll syntheses Fulltext Access 9 Pages 2015
Cellular localization of β-carotene 15,15â² oxygenase-1 (BCO1) and β-carotene 9â²,10â² oxygenase-2 (BCO2) in rat liver and intestine Fulltext Access 9 Pages 2015
Actions of β-apo-carotenoids in differentiating cells: Differential effects in P19 cells and 3T3-L1 adipocytes Fulltext Access 9 Pages 2015
An integrated view of redox and catalytic properties of B-type PpDyP from Pseudomonas putida MET94 and its distal variants Fulltext Access 9 Pages 2015
Basidiomycete DyPs: Genomic diversity, structural-functional aspects, reaction mechanism and environmental significance Fulltext Access 9 Pages 2015
Functional characterization of three (GH13) branching enzymes involved in cyanobacterial starch biosynthesis from Cyanobacterium sp. NBRC 102756 Fulltext Access 9 Pages 2015
Activity of 1,3-β-D-Glucanases and Expression of CG-GLU1 in the Mussel Crenomytilus grayanus (Bivalvia) in Three Bays of the Sea of Japan Fulltext Access 9 Pages 2015
Tumor growth delay by adjuvant alternating electric fields which appears non-thermally mediated Fulltext Access 9 Pages 2015
DNA Functionalized Direct Electro-deposited Gold nanoaggregates for Efficient Detection of Salmonella typhi Fulltext Access 9 Pages 2015
E. coli electroeradication on a closed loop circuit by using milli-, micro- and nanosecond pulsed electric fields: Comparison between energy costs Fulltext Access 9 Pages 2015
Maintenance of Geobacter-dominated biofilms in microbial fuel cells treating synthetic wastewater Fulltext Access 9 Pages 2015
Hydrogen bioelectrooxidation on gold nanoparticle-based electrodes modified by Aquifex aeolicus hydrogenase: Application to hydrogen/oxygen enzymatic biofuel cells Fulltext Access 9 Pages 2015
A novel third generation uric acid biosensor using uricase electro-activated with ferrocene on a Nafion coated glassy carbon electrode Fulltext Access 9 Pages 2015
Endocytic pH regulates cell surface localization of glycolipid antigen loaded CD1d complexes Fulltext Access 9 Pages 2015
Pulmonary Endothelial Cell Barrier Enhancement by Novel FTY720 Analogs: Methoxy-FTY720, Fluoro-FTY720, and β-Glucuronide-FTY720 Fulltext Access 9 Pages 2015
Pathway-centric analysis of the DNA damage response to chemotherapeutic agents in two breast cell lines Fulltext Access 9 Pages 2015
Abdominal vasculature in dynamic contrast-enhanced liver MRI at 3.0 T: an intraindividual comparative study using gadoxetate disodium and gadofosveset trisodium Fulltext Access 9 Pages 2015
Multidimensional electrostatic repulsion–hydrophilic interaction chromatography (ERLIC) for quantitative analysis of the proteome and phosphoproteome in clinical and biomedical research Fulltext Access 9 Pages 2015
A key lysine residue in the AXH domain of ataxin-1 is essential for its ubiquitylation Fulltext Access 9 Pages 2015
Proteomic profiling in MPTP monkey model for early Parkinson disease biomarker discovery Fulltext Access 9 Pages 2015
Monocytic elastase-mediated apolipoprotein-E degradation: Potential involvement of microglial elastase-like proteases in apolipoprotein-E proteolysis in brains with Alzheimers disease Fulltext Access 9 Pages 2015
The kinetic characterization and X-ray structure of a putative benzoylformate decarboxylase from M. smegmatis highlights the difficulties in the functional annotation of ThDP-dependent enzymes Fulltext Access 9 Pages 2015
Multiple low-affinity interactions support binding of human osteopontin to integrin αXβ2 Fulltext Access 9 Pages 2015
Mutation of Gly717Phe in human topoisomerase 1B has an effect on enzymatic function, reactivity to the camptothecin anticancer drug and on the linker domain orientation Fulltext Access 9 Pages 2015
Dissociation of a BRICHOS trimer into monomers leads to increased inhibitory effect on Aβ42 fibril formation Fulltext Access 9 Pages 2015
Ultrasonication-dependent formation and degradation of α-synuclein amyloid fibrils Fulltext Access 9 Pages 2015
A new role for sphingosine: Up-regulation of Fam20C, the genuine casein kinase that phosphorylates secreted proteins Fulltext Access 9 Pages 2015
An anthropomorphic multimodality (CT/MRI) head phantom prototype for end-to-end tests in ion radiotherapy Fulltext Access 9 Pages 2015
The conserved core enzymatic activities and the distinct dynamics of polyomavirus large T antigens Fulltext Access 9 Pages 2015
Aberrant movement of β-tropomyosin associated with congenital myopathy causes defective response of myosin heads and actin during the ATPase cycle Fulltext Access 9 Pages 2015
Transmission electron microscopy and the molecular structure of icosahedral viruses Fulltext Access 9 Pages 2015
Secreted lipoxygenase from Pseudomonas aeruginosa exhibits biomembrane oxygenase activity and induces hemolysis in human red blood cells Fulltext Access 9 Pages 2015
Probing the chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae using site-directed mutagenesis Fulltext Access 9 Pages 2015
Solution structure and base specificity of cytotoxic RC-RNase 2 from Rana catesbeiana Fulltext Access 9 Pages 2015
Functional importance of a peripheral pocket in mammalian cytochrome P450 2B enzymes Fulltext Access 9 Pages 2015
Key roles of Tyr 10 in Cu bound Aβ complexes and its relevance to Alzheimer's disease Fulltext Access 9 Pages 2015
Electrostatics effects on Ca2+ binding and conformational changes in EF-hand domains: Functional implications for EF-hand proteins Fulltext Access 9 Pages 2015
PD150606 protects against ischemia/reperfusion injury by preventing μ-calpain-induced mitochondrial apoptosis Fulltext Access 9 Pages 2015
Biochemical and biophysical characterization of maize-derived HBsAg for the development of an oral vaccine Fulltext Access 9 Pages 2015
Correlation of oxygenation and perfusion sensitive MRI with invasive micro probe measurements in healthy mice brain Fulltext Access 9 Pages 2015
Simulation study of the effect of golden-angle KWIC with generalized kinetic model analysis on diagnostic accuracy for lesion discrimination Fulltext Access 9 Pages 2015
Enhancement parameters on dynamic contrast enhanced breast MRI: do they correlate with prognostic factors and subtypes of breast cancers? Fulltext Access 9 Pages 2015
Engineering for safety assurance in MRI: analytical, numerical and experimental dosimetry Fulltext Access 9 Pages 2015
Value of apparent diffusion coefficient (ADC) in assessing radiotherapy and chemotherapy success in cervical cancer Fulltext Access 9 Pages 2015
MRI investigation of water–oil two phase flow in straight capillary, bifurcate channel and monolayered glass bead pack Fulltext Access 9 Pages 2015
Quantitative pharmacokinetic analysis of prostate cancer DCE-MRI at 3 T: comparison of two arterial input functions on cancer detection with digitized whole mount histopathological validation Fulltext Access 9 Pages 2015
Dose and pulse sequence considerations for hyperpolarized 129Xe ventilation MRI Fulltext Access 9 Pages 2015
Nuclear-Overhauser-enhanced MR imaging of 31P-containing metabolites: multipoint-Dixon vs. frequency-selective excitation Fulltext Access 9 Pages 2015