Structural Insights into the Mechanisms of Drug Resistance in HIV-1 Protease NL4-3 Fulltext Access 15 Pages 2006
Structural Basis of the Differential Stability and Receptor Specificity of H-2Db in Complex with Murine versus Human β2-Microglobulin Fulltext Access 15 Pages 2006
Crystal Structure of a Glycyl Radical Enzyme from Archaeoglobus fulgidus Fulltext Access 15 Pages 2006
X-ray Structures of Free and Leupeptin-complexed Human αI-Tryptase Mutants: Indication for an α→β-Tryptase Transition Fulltext Access 15 Pages 2006
Tyrosine Plays a Dominant Functional Role in the Paratope of a Synthetic Antibody Derived from a Four Amino Acid Code Fulltext Access 15 Pages 2006
The Disaggregation Activity of the Mitochondrial ClpB Homolog Hsp78 Maintains Hsp70 Function during Heat Stress Fulltext Access 15 Pages 2006
Translation of Sindbis Virus 26 S mRNA Does Not Require Intact Eukariotic Initiation Factor 4G Fulltext Access 15 Pages 2006
Cytoplasmic Shuttling of Protons in Anabaena Sensory Rhodopsin: Implications for Signaling Mechanism Fulltext Access 15 Pages 2006
Structural Basis for the Substrate Specificity of a Bacillus 1,3-1,4-β-Glucanase Fulltext Access 15 Pages 2006
Dimerisation and an Increase in Active Site Aromatic Groups as Adaptations to High Temperatures: X-ray Solution Scattering and Substrate-bound Crystal Structures of Rhodothermus marinus Endoglucanase Cel12A Fulltext Access 15 Pages 2006
Molecular Dynamics Simulations and Free Energy Analyses on the Dimer Formation of an Amyloidogenic Heptapeptide from Human β2-Microglobulin: Implication for the Protofibril Structure Fulltext Access 15 Pages 2006
The Solution Structure of the Native K50 Bicoid Homeodomain Bound to the Consensus TAATCC DNA-binding Site Fulltext Access 15 Pages 2006
Selective Pressures at a Codon-level Predict Deleterious Mutations in Human Disease Genes Fulltext Access 15 Pages 2006
A Novel Processive Mechanism for DNA Synthesis Revealed by Structure, Modeling and Mutagenesis of the Accessory Subunit of Human Mitochondrial DNA Polymerase Fulltext Access 15 Pages 2006
Molecular Determinants for Substrate Specificity of the Ligand-binding Protein OpuAC from Bacillus subtilis for the Compatible Solutes Glycine Betaine and Proline Betaine Fulltext Access 15 Pages 2006
TCP34, a Nuclear-encoded Response Regulator-like TPR Protein of Higher Plant Chloroplasts Fulltext Access 15 Pages 2006
Co-repressor Induced Order and Biotin Repressor Dimerization: A Case for Divergent Followed by Convergent Evolution Fulltext Access 15 Pages 2006
On the Mechanism of Sequence-specific DNA-dependent Acetylation of p53: The Acetylation Motif is Exposed upon DNA Binding Fulltext Access 15 Pages 2006
Direct Selection of Antibodies from Complex Libraries with the Protein Fragment Complementation Assay Fulltext Access 15 Pages 2006
Detecting Molecular Interactions that Stabilize Native Bovine Rhodopsin Fulltext Access 15 Pages 2006
Channel Opening Motion of α7 Nicotinic Acetylcholine Receptor as Suggested by Normal Mode Analysis Fulltext Access 15 Pages 2006
Archaeal RNA Polymerase is Sensitive to Intrinsic Termination Directed by Transcribed and Remote Sequences Fulltext Access 15 Pages 2006
Gata3 is required for early morphogenesis and Fgf10 expression during otic development Fulltext Access 15 Pages 2006
Labeled lines in the retinotectal system: Markers for retinorecipient sublaminae and the retinal ganglion cell subsets that innervate them Fulltext Access 15 Pages 2006
Brain-derived neurotrophic factor-induced potentiation of glutamate and GABA release: Different dependency on signaling pathways and neuronal activity Fulltext Access 15 Pages 2006
Synaptic activity and F-actin coordinately regulate CaMKIIα localization to dendritic postsynaptic sites in developing hippocampal slices Fulltext Access 15 Pages 2006
Up-regulation and increased phosphorylation of protein kinase C (PKC) δ, μ and θ in the degenerating rd1 mouse retina Fulltext Access 15 Pages 2006
Brain-specific factors in combination with mutant huntingtin induce gene-specific transcriptional dysregulation Fulltext Access 15 Pages 2006
Unraveling the differential expression of the two isoforms of myelin-associated glycoprotein in a mouse expressing GFP-tagged S-MAG specifically regulated and targeted into the different myelin compartments Fulltext Access 15 Pages 2006
A unique subpopulation of Tbr1-expressing deep layer neurons in the developing cerebral cortex Fulltext Access 15 Pages 2006
GSK3β and PKCζ function in centrosome localization and process stabilization during Slit-mediated neuronal repolarization Fulltext Access 15 Pages 2006
Characterization of epidermal neural crest stem cell (EPI-NCSC) grafts in the lesioned spinal cord Fulltext Access 15 Pages 2006
Female sexual maturation and reproduction after prepubertal exposure to estrogens and endocrine disrupting chemicals: A review of rodent and human data Fulltext Access 15 Pages 2006
Independent roles of Drosophila Moesin in imaginal disc morphogenesis and hedgehog signalling Fulltext Access 15 Pages 2006
I-BasI and I-HmuI: Two Phage Intron-encoded Endonucleases with Homologous DNA Recognition Sequences but Distinct DNA Specificities Fulltext Access 15 Pages 2006
Visualization of the Xenopus primordial germ cells using a green fluorescent protein controlled by cis elements of the 3′ untranslated region of the DEADSouth gene Fulltext Access 15 Pages 2006
smoothened, thickveins and the genetic control of cell cycle and cell fate in the developing Drosophila eye Fulltext Access 15 Pages 2006
Temporal requirement for bone morphogenetic proteins in regeneration of the tail and limb of Xenopus tadpoles Fulltext Access 15 Pages 2006
Structure of an otter (Lutra lutra) population in Germany – results of DNA and hormone analyses from faecal samples Fulltext Access 15 Pages 2006
Genetic structure, habitat fragmentation and bottlenecks in Danish bank voles (Clethrionomys glareolus) Fulltext Access 15 Pages 2006
Actin Interacts with CCT via Discrete Binding Sites: A Binding transition-release Model for CCT-Mediated Actin Folding Fulltext Access 15 Pages 2006
Epitope Diversity of Hepatitis B Virus Capsids: Quasi-equivalent Variations in Spike Epitopes and Binding of Different Antibodies to the same Epitope Fulltext Access 15 Pages 2006
Structural Basis for the Requirement of Two Phosphotyrosine Residues in Signaling Mediated by Syk Tyrosine Kinase Fulltext Access 15 Pages 2006
Effects of Solubilization on the Structure and Function of the Sensory Rhodopsin II/Transducer Complex Fulltext Access 15 Pages 2006
The diaphanous-related formin DAAM1 collaborates with the Rho GTPases RhoA and Cdc42, CIP4 and Src in regulating cell morphogenesis and actin dynamics Fulltext Access 15 Pages 2006
Hepatocyte Nuclear Factor 4 Alpha Ligand Binding and F Domains Mediate Interaction and Transcriptional Synergy with the Pancreatic Islet LIM HD Transcription Factor Isl1 Fulltext Access 15 Pages 2006
Residue-level NMR View of the Urea-driven Equilibrium Folding Transition of SUMO-1 (1-97): Native Preferences Do Not Increase Monotonously Fulltext Access 15 Pages 2006
Interplay Between Metal Binding and cis/trans Isomerization in Legume Lectins: Structural and Thermodynamic Study of P. angolensis Lectin Fulltext Access 15 Pages 2006
Co-evolutionary Analysis of Domains in Interacting Proteins Reveals Insights into Domain–Domain Interactions Mediating Protein–Protein Interactions Fulltext Access 15 Pages 2006
Biochemical Analysis of a DNA Replication Origin in the Archaeon Aeropyrum pernix Fulltext Access 15 Pages 2006
Quantitative Evaluation of Each Catalytic Subsite of Cathepsin B for Inhibitory Activity Based on Inhibitory Activity–Binding Mode Relationship of Epoxysuccinyl Inhibitors by X-ray Crystal Structure Analyses of Complexes Fulltext Access 15 Pages 2006
Structural Basis for Rab11-mediated Recruitment of FIP3 to Recycling Endosomes Fulltext Access 15 Pages 2006
Cell signaling pathways to αB-crystallin following stresses of the cytoskeleton Fulltext Access 15 Pages 2006
Dopamine-related and caspase-independent apoptosis in dopaminergic neurons induced by overexpression of human wild type or mutant α-synuclein Fulltext Access 15 Pages 2006
MEGAP impedes cell migration via regulating actin and microtubule dynamics and focal complex formation Fulltext Access 15 Pages 2006
Bach2 is involved in neuronal differentiation of N1E-115 neuroblastoma cells Fulltext Access 15 Pages 2006
Structure, Dynamics and Heparin Binding of the C-terminal Domain of Insulin-like Growth Factor-binding Protein-2 (IGFBP-2) Fulltext Access 15 Pages 2006
The coxsackie- and adenovirus receptor (CAR) is an in vivo marker for epithelial tight junctions, with a potential role in regulating permeability and tissue homeostasis Fulltext Access 15 Pages 2006
HaCaT keratinocyte migration is dependent on epidermal growth factor receptor signaling and glycogen synthase kinase-3α Fulltext Access 15 Pages 2006
The Rothmund-Thomson gene product RECQL4 localizes to the nucleolus in response to oxidative stress Fulltext Access 15 Pages 2006
Junctional adhesion molecule-A participates in the formation of apico-basal polarity through different domains Fulltext Access 15 Pages 2006
ROCK signaling mediates the adoption of different modes of migration and invasion in human mammary epithelial tumor cells Fulltext Access 15 Pages 2006
Neural regeneration protein is a novel chemoattractive and neuronal survival-promoting factor Fulltext Access 15 Pages 2006
Specific deletion of CMF1 nuclear localization domain causes incomplete cell cycle withdrawal and impaired differentiation in avian skeletal myoblasts Fulltext Access 15 Pages 2006
Interleukin-4 improves the migration of human myogenic precursor cells in vitro and in vivo Fulltext Access 15 Pages 2006
Alfalfa Mob1-like proteins are involved in cell proliferation and are localized in the cell division plane during cytokinesis Fulltext Access 15 Pages 2006
Dissociation of ERK and Akt signaling in endothelial cell angiogenic responses to β-amyloid Fulltext Access 15 Pages 2006
Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation Fulltext Access 15 Pages 2006
Transcriptional Repressor CcpN from Bacillus subtilis Compensates Asymmetric Contact Distribution by Cooperative Binding Fulltext Access 15 Pages 2006
The Chemotaxis Response Regulator CheY Can Catalyze its Own Acetylation Fulltext Access 15 Pages 2006
Thermodynamic and Kinetic Characterization of Ligand Binding to the Purine Riboswitch Aptamer Domain Fulltext Access 15 Pages 2006
Structural Snapshots of β-1,4-Galactosyltransferase-I Along the Kinetic Pathway Fulltext Access 15 Pages 2006
Communication Between Accessory Factors and the Cre Recombinase at Hybrid psi-loxP sites Fulltext Access 15 Pages 2006
The Folding Pathway of Spectrin R17 from Experiment and Simulation: Using Experimentally Validated MD Simulations to Characterize States Hinted at by Experiment Fulltext Access 15 Pages 2006
Crystal Structures of the Lytic Transglycosylase MltA from N. gonorrhoeae and E. coli: Insights into Interdomain Movements and Substrate Binding Fulltext Access 15 Pages 2006
Comprehensive Analysis of Combinatorial Regulation using the Transcriptional Regulatory Network of Yeast Fulltext Access 15 Pages 2006
Hijacking of a Substrate-binding Protein Scaffold for use in Mycobacterial Cell Wall Biosynthesis Fulltext Access 15 Pages 2006
Assembly of Infectious HIV-1 in Human Epithelial and T-Lymphoblastic Cell Lines Fulltext Access 15 Pages 2006
Φ-Analysis of the Folding of the B Domain of Protein A Using Multiple Optical Probes Fulltext Access 15 Pages 2006
Dynamics of Mutation and Recombination in a Replicating Population of Complementing, Defective Viral Genomes Fulltext Access 15 Pages 2006
Catalog of gene expression in adult neural stem cells and their in vivo microenvironment Fulltext Access 15 Pages 2006
Evaluation of Energetic and Dynamic Coupling Networks in a PDZ Domain Protein Fulltext Access 15 Pages 2006
Functional and Structural Characterization of HIV-1 gp41 Ectodomain Regions in Phospholipid Membranes Suggests that the Fusion-active Conformation Is Extended Fulltext Access 15 Pages 2006
Characterization of MobR, the 3-Hydroxybenzoate-responsive Transcriptional Regulator for the 3-Hydroxybenzoate Hydroxylase Gene of Comamonas testosteroni KH122-3s Fulltext Access 15 Pages 2006
Activation of the Proapoptotic Death Receptor DR5 by Oligomeric Peptide and Antibody Agonists Fulltext Access 15 Pages 2006
A Dimeric Kinase Assembly Underlying Autophosphorylation in the p21 Activated Kinases Fulltext Access 15 Pages 2006
In Vitro and in Vivo Nucleosome Positioning on the Ovine β-Lactoglobulin Gene Are Related Fulltext Access 15 Pages 2006
Three-dimensional Structure of a Type III Glutamine Synthetase by Single-particle Reconstruction Fulltext Access 15 Pages 2006
Kinetics of ATP-stimulated Nuclease Activity of the Escherichia coli RecBCD Enzyme Fulltext Access 15 Pages 2006
The Structure of Apo-wild-type Cellular Retinoic Acid Binding Protein II at 1.4 Å and its Relationship to Ligand Binding and Nuclear Translocation Fulltext Access 15 Pages 2006