Hepatic stellate cells display a functional vascular smooth muscle cell phenotype in a three-dimensional co-culture model with endothelial cells Fulltext Access 11 Pages 2008
Human neural progenitor cells derived from embryonic stem cells in feeder-free cultures Fulltext Access 11 Pages 2008
Interdependent fibroblast growth factor and activin A signaling promotes the expression of endodermal genes in differentiating mouse embryonic stem cells expressing Src Homology 2-domain inactive Shb Fulltext Access 11 Pages 2008
MBNL3/CHCR prevents myogenic differentiation by inhibiting MyoD-dependent gene transcription Fulltext Access 11 Pages 2008
A ubiquitin-conjugating enzyme, ube2d3.2, regulates xMLK2 and pronephros formation in Xenopus Fulltext Access 11 Pages 2008
Induction of pancreatic islet cell differentiation by the neurogenin–neuroD cascade Fulltext Access 11 Pages 2008
Development of a multipotent clonal human periodontal ligament cell line Fulltext Access 11 Pages 2008
Prospective isolation and characterization of mesenchymal stem cells from human placenta using a frizzled-9-specific monoclonal antibody Fulltext Access 11 Pages 2008
Peripheral sensory neurons differentiate from neural precursors derived from human embryonic stem cells Fulltext Access 11 Pages 2008
Hedgehog signals in pancreatic differentiation from embryonic stem cells: revisiting the neglected Fulltext Access 11 Pages 2008
Inhibition of monoamine oxidase A promotes secretory differentiation in basal prostatic epithelial cells Fulltext Access 11 Pages 2008
Periostin expression by epicardium-derived cells is involved in the development of the atrioventricular valves and fibrous heart skeleton Fulltext Access 11 Pages 2008
Multipotent cells from the human third molar: feasibility of cell-based therapy for liver disease Fulltext Access 11 Pages 2008
Integrating differentiation and cancer: The Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis Fulltext Access 11 Pages 2008
Retinoid signaling can repress blastula Wnt signaling and impair dorsal development in Xenopus embryo Fulltext Access 11 Pages 2008
Vasculogeneic maturation of E14 embryonic stem cells with evidence of early vascular endothelial growth factor independency Fulltext Access 11 Pages 2008
An immediate–early gene, srsA: its involvement in the starvation response that initiates differentiation of Dictyostelium cells Fulltext Access 11 Pages 2008
Leukemia inhibitory factor contributes to hepatocyte-like differentiation of human bone marrow mesenchymal stem cells Fulltext Access 11 Pages 2008
Declining cellular fitness with age promotes cancer initiation by selecting for adaptive oncogenic mutations Fulltext Access 11 Pages 2008
When 2 + 2 = 5: The origins and fates of aneuploid and tetraploid cells Fulltext Access 11 Pages 2008
Proteases as modulators of tumor–stromal interaction: Primary tumors to bone metastases Fulltext Access 11 Pages 2008
CAPS1 and CAPS2 Regulate Stability and Recruitment of Insulin Granules in Mouse Pancreatic β Cells Fulltext Access 11 Pages 2008
Functional characterisation of the Schizosaccharomyces pombe homologue of the leukaemia-associated translocation breakpoint binding protein translin and its binding partner, TRAX Fulltext Access 11 Pages 2008
Enhanced ubiquitin-proteasome activity in calreticulin deficient cells: A compensatory mechanism for cell survival Fulltext Access 11 Pages 2008
The nuclear localization of Drosophila Hsp27 is dependent on a monopartite arginine-rich NLS and is uncoupled from its association to nuclear speckles Fulltext Access 11 Pages 2008
A presynaptically toxic secreted phospholipase A2 is internalized into motoneuron-like cells where it is rapidly translocated into the cytosol Fulltext Access 11 Pages 2008
The sodium pump Ena1p provides mechanistic insight into the salt sensitivity of vacuolar protein sorting mutants Fulltext Access 11 Pages 2008
Extracellular annexin A5: Functions of phosphatidylserine-binding and two-dimensional crystallization Fulltext Access 11 Pages 2008
RETRACTED: The Hepcidin-Binding Site on Ferroportin Is Evolutionarily Conserved Fulltext Access 11 Pages 2008
RBP4 Disrupts Vitamin A Uptake Homeostasis in a STRA6-Deficient Animal Model for Matthew-Wood Syndrome Fulltext Access 11 Pages 2008
The Acyclic CB1R Inverse Agonist Taranabant Mediates Weight Loss by Increasing Energy Expenditure and Decreasing Caloric Intake Fulltext Access 11 Pages 2008
PDK1 Deficiency in POMC-Expressing Cells Reveals FOXO1-Dependent and -Independent Pathways in Control of Energy Homeostasis and Stress Response Fulltext Access 11 Pages 2008
The Insulin-Regulated CREB Coactivator TORC Promotes Stress Resistance in Drosophila Fulltext Access 11 Pages 2008
HDL, ABC Transporters, and Cholesterol Efflux: Implications for the Treatment of Atherosclerosis Fulltext Access 11 Pages 2008
Adipocyte-Derived Th2 Cytokines and Myeloid PPARδ Regulate Macrophage Polarization and Insulin Sensitivity Fulltext Access 11 Pages 2008
Chronic Stretching of Amniotic Epithelial Cells Increases Pre-B Cell Colony-Enhancing Factor (PBEF/Visfatin) Expression and Protects Them from Apoptosis Fulltext Access 11 Pages 2008
Morphological and Electrical Properties of Human Trophoblast Choriocarcinoma, BeWo Cells Fulltext Access 11 Pages 2008
Vitamins C and E Inhibit Apoptosis of Cultured Human Term Placenta Trophoblast Fulltext Access 11 Pages 2008
Somatostatin as a Regulator of First-Trimester Human Trophoblast Functions Fulltext Access 11 Pages 2008
MARCKS is a downstream effector in platelet-derived growth factor-induced cell motility in activated human hepatic stellate cells Fulltext Access 11 Pages 2008
Synthesis of novel aminoquinonoid analogues of diospyrin and evaluation of their inhibitory activity against murine and human cancer cells Fulltext Access 11 Pages 2008
Synthesis, antimicrobial activity, pharmacophore analysis of some new 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles Fulltext Access 11 Pages 2008
A molecular model of a putative substrate releasing conformation of multidrug resistance protein 5 (MRP5) Fulltext Access 11 Pages 2008
Synthesis and evaluation of fluoroquinolone derivatives as substrate-based inhibitors of bacterial efflux pumps Fulltext Access 11 Pages 2008
Towards predictive inhibitor design for the EGFR autophosphorylation activity Fulltext Access 11 Pages 2008
Synthesis and in vitro antibacterial activities of novel oxazolidinones Fulltext Access 11 Pages 2008
A new class of analgesic agents toward prostacyclin receptor inhibition: Synthesis, biological studies and QSAR analysis of 1-hydroxyl-2-substituted phenyl-4,4,5,5-tetramethylimidazolines Fulltext Access 11 Pages 2008
Aldehyde dehydrogenase inhibitors: α,β-Acetylenic N-substituted aminothiolesters are reversible growth inhibitors of normal epithelial but irreversible apoptogens for cancer epithelial cells from human prostate in culture Fulltext Access 11 Pages 2008
QSAR analysis of 1,3-diaryl-4,5,6,7-tetrahydro-2H-isoindole derivatives as selective COX-2 inhibitors Fulltext Access 11 Pages 2008
Syntheses of 4-(indole-3-yl)quinazolines – A new class of epidermal growth factor receptor tyrosine kinase inhibitors Fulltext Access 11 Pages 2008
In silico screening of HIV-1 non-nucleoside reverse transcriptase and protease inhibitors Fulltext Access 11 Pages 2008
CODES, a novel procedure for ligand-based virtual screening: PDE7 inhibitors as an application example Fulltext Access 11 Pages 2008
Synthesis, spectral characterization, in vitro antibacterial, antifungal and cytotoxic activities of Co(II), Ni(II) and Cu(II) complexes with 1,2,4-triazole Schiff bases Fulltext Access 11 Pages 2008
Structure–activity relationships of novel heteroaryl-acrylonitriles as cytotoxic and antibacterial agents Fulltext Access 11 Pages 2008
Activity of a hydroxybibenzyl bryophyte constituent against Leishmania spp. and Trypanosoma cruzi: In silico, in vitro and in vivo activity studies Fulltext Access 11 Pages 2008
Synthesis and biological activities of some new fluorinated coumarins and 1-aza coumarins Fulltext Access 11 Pages 2008
Synthesis and biological evaluation of amide derivatives of (5,6-dimethoxy-2,3-dihydro-1H-inden-1-yl)acetic acid as anti-inflammatory agents with reduced gastrointestinal ulcerogenecity Fulltext Access 11 Pages 2008
Condensed bridgehead nitrogen heterocyclic system: Synthesis and pharmacological activities of 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives of ibuprofen and biphenyl-4-yloxy acetic acid Fulltext Access 11 Pages 2008
Synthesis and antimalarial activity of carbamate and amide derivatives of 4-anilinoquinoline Fulltext Access 11 Pages 2008
Proteomic analysis of exhaled breath condensate from single patients with pulmonary emphysema associated to α1-antitrypsin deficiency Fulltext Access 11 Pages 2008
Aldehyde dehydrogenase 1A1 and gelsolin identified as novel invasion-modulating factors in conditioned medium of pancreatic cancer cells Fulltext Access 11 Pages 2008
Evaluation of a standardized method of protein purification and identification after discovery by mass spectrometry Fulltext Access 11 Pages 2008
N-[2-(5,5-Dimethyl-1,3-dioxane-2-yl)ethyl]amino acids: Their synthesis, anti-inflammatory evaluation and QSAR analysis Fulltext Access 11 Pages 2008
Structural analysis of interphase X-chromatin based on statistical shape theory Fulltext Access 11 Pages 2008
Mitochondrial H2O2 limits U937 cell survival to peroxynitrite by promoting ERK1/2 dephosphorylation Fulltext Access 11 Pages 2008
Nuclear translocation of hypoxia-inducible factors (HIFs): Involvement of the classical importin α/β pathway Fulltext Access 11 Pages 2008
KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling Fulltext Access 11 Pages 2008
Function and redox state of mitochondrial localized cysteine-rich proteins important in the assembly of cytochrome c oxidase Fulltext Access 11 Pages 2008
Building and operating an antibody factory: Redox control during B to plasma cell terminal differentiation Fulltext Access 11 Pages 2008
Galectin-3 but not galectin-1 induces mast cell death by oxidative stress and mitochondrial permeability transition Fulltext Access 11 Pages 2008
New cerium(III) complexes of coumarins – Synthesis, characterization and cytotoxicity evaluation Fulltext Access 11 Pages 2008
Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: A critical revisitation Fulltext Access 11 Pages 2008
Synthesis and antiprotozoal activities of simplified analogs of naphthylisoquinoline alkaloids Fulltext Access 11 Pages 2008
Novel Pd(II) complexes of 1-N-substituted 3-phenyl-2-pyrazoline derivatives and evaluation of antiamoebic activity Fulltext Access 11 Pages 2008
Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of pyrrolo[3,4-a]carbazole-1,3-diones, pyrrolo[3,4-c]carbazole-1,3-diones, and 2-aminopyridazino[3,4-a]pyrrolo[3,4-c]carbazole-1,3,4,7-tetraone Fulltext Access 11 Pages 2008
Design and microwave-assisted synthesis of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles: Novel agents with analgesic and anti-inflammatory properties Fulltext Access 11 Pages 2008
Synthesis, anti-HIV-1 integrase, and cytotoxic activities of 4-chloro-N-(4-oxopyrimidin-2-yl)-2-mercaptobenzenesulfonamide derivatives Fulltext Access 11 Pages 2008
Syntheses of tetrahydroisoquinoline derivatives that inhibit NO production in activated BV-2 microglial cells Fulltext Access 11 Pages 2008
Structure–activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues Fulltext Access 11 Pages 2008
1,8-Naphthyridines VI. Synthesis and anti-inflammatory activity of 5-(alkylamino)-N,N-diethyl[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides with a new substitution pattern on the triazole ring Fulltext Access 11 Pages 2008
Three-dimensional QSAR analyses of 1,3,4-trisubstituted pyrrolidine-based CCR5 receptor inhibitors Fulltext Access 11 Pages 2008
1,3,4-Oxadiazole/thiadiazole and 1,2,4-triazole derivatives of biphenyl-4-yloxy acetic acid: Synthesis and preliminary evaluation of biological properties Fulltext Access 11 Pages 2008
Structure–activity relationships in the acronycine and benzo[b]acronycine series: Role of the pyran ring Fulltext Access 11 Pages 2008