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Daneshyari Molecular Medicine Journas Latest Articles

Molecular Medicine Research Articles

Effect of coenzyme Q10 intake on endogenous coenzyme Q content, mitochondrial electron transport chain, antioxidative defenses, and life span of mice
Fulltext Access 8 Pages 2006
Hereditary hyperferritinemia cataract syndrome in three unrelated families of western Greek origin caused by the C39 > G mutation of L-ferritin IRE
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Mining the oocyte transcriptome
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B cells in the spotlight: innocent bystanders or major players in the pathogenesis of type 1 diabetes
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Lessons from peroxisome-deficient Chinese hamster ovary (CHO) cell mutants
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Mechanisms of H2O2-induced oxidative stress in endothelial cells
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Carbon monoxide and biliverdin prevent endothelial cell sloughing in rats with type I diabetes
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Silent information regulator 2 (SIRT1) attenuates oxidative stress-induced mesangial cell apoptosis via p53 deacetylation
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Oxygen-sensitive reset of hypoxia-inducible factor transactivation response: Prolyl hydroxylases tune the biological normoxic set point
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Plasma nitrite concentrations reflect the degree of endothelial dysfunction in humans
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Early determinants of H2O2-induced endothelial dysfunction
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Effects of ectopic expression of Drosophila DNA glycosylases dOgg1 and RpS3 in mitochondria
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Total nitrogen oxide following exercise testing reflects endothelial function and discriminates health status
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A novel R416C mutation in human DMT1 (SLC11A2) displays pleiotropic effects on function and causes microcytic anemia and hepatic iron overload
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Free zinc inhibits transport of vitamin C in differentiated HL-60 cells during respiratory burst
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Acute administration of vitamin E triggers preconditioning via KATP channels and cyclic-GMP without inhibiting lipid peroxidation
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The confounding effects of light, sonication, and Mn(III)TBAP on quantitation of superoxide using hydroethidine
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Carcinogenic 3-nitrobenzanthrone induces oxidative damage to isolated and cellular DNA
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Tamoxifen protects against acute tumor necrosis factor α-induced cardiac injury via improving mitochondrial functions
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Glycolaldehyde induces growth inhibition and oxidative stress in human breast cancer cells*
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Evaluation of enzyme-linked immunosorbent assay and liquid chromatography–tandem mass spectrometry methodology for the analysis of 8-oxo-7,8-dihydro-2′-deoxyguanosine in saliva and urine
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Plasma very-low-density lipoprotein, low-density lipoprotein, and high-density lipoprotein oxidative modification induces procoagulant profiles in endogenous hypertriglyceridemia
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Apomorphine-induced myocardial protection is due to antioxidant and not adrenergic/dopaminergic effects
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Hydrogen peroxide restrains endothelium-derived nitric oxide bioactivity—Role for iron-dependent oxidative stress
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Studies of an active site mutant of the selenoprotein thioredoxin reductase: The Ser-Cys-Cys-Ser motif of the insect orthologue is not sufficient to replace the Cys-Sec dyad in the mammalian enzyme
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Protein farnesyltransferase inhibitors and progeria
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From deafness genes to hearing mechanisms: harmony and counterpoint
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Defective translation initiation causes vanishing of cerebral white matter
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Hypervitaminosis D and premature aging: lessons learned from Fgf23 and Klotho mutant mice
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Signal transduction induced by activated protein C: no role in protection against sepsis?
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The IGF-1 network in lung carcinoma therapeutics
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MicroRNA expression and function in cancer
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Drug addiction: the neurobiology of disrupted self-control
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Activation-induced deaminase: light and dark sides
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Deconstructing the molecular portrait of basal-like breast cancer
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Evidence of recurrent gene fusions in common epithelial tumors
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Understanding the molecular causes of Parkinson's disease
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Utrophin upregulation for treating Duchenne or Becker muscular dystrophy: how close are we?
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Oxidatively modified autoantigens in autoimmune diseases
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MHC–peptide specificity and T-cell epitope mapping: where immunotherapy starts
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Human cytomegalovirus vaccine: time to look for alternative options
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The role of apoptosis in neuromuscular diseases and prospects for anti-apoptosis therapy
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Translating m-AAA protease function in mitochondria to hereditary spastic paraplegia
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New insights into the pathophysiology of cobalamin deficiency
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A concise review of DNA damage checkpoints and repair in mammalian cells
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Podocalyxin is expressed in normal and leukemic monocytes
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The proteomic study of sodium butyrate antiproliferative/cytodifferentiation effects on K562 cells
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Membrane skeletal protein S-glutathionylation and hemolysis in human red blood cells
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Blood cells as targets of snake toxins
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Retinoic acid-induced protein ISGylation is dependent on interferon signal transduction
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In vivo contribution of Class III alcohol dehydrogenase (ADH3) to alcohol metabolism through activation by cytoplasmic solution hydrophobicity
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Suppression of UVA-mediated release of labile iron by epicatechin—A link to lysosomal protection
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8-Isoprostane-induced endothelin-1 production by infant rat pulmonary artery smooth muscle cells is mediated by Rho-kinase
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Redox proteomic identification of oxidized cardiac proteins in Adriamycin-treated mice
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Oxidation-induced changes in human lens epithelial cells: 1. Phospholipids
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Reduction in extracellular superoxide dismutase activity in African-American patients with hypertension
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Xanthine oxidase inhibitor tungsten prevents the development of atherosclerosis in ApoE knockout mice fed a Western-type diet
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Association between nitric oxide synthesis and vaccination-acquired resistance to murine hepatitis virus by spf mice
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Antigen presenting cells (APCs) from thermally injured and/or septic rats modulate CD4+ T cell responses of naive rat
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Brain-specific change in alternative splicing of Tau exon 6 in myotonic dystrophy type 1
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The relevance of mitochondrial membrane topology to mitochondrial function
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Combination therapy using minocycline and coenzyme Q10 in R6/2 transgenic Huntington's disease mice
Fulltext Access 8 Pages 2006
A study of the nuclear trafficking of the splicing factor protein PRPF31 linked to autosomal dominant retinitis pigmentosa (ADRP)
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Sunscreen enhancement of UV-induced reactive oxygen species in the skin
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Overexpression of CXCL10 in human prostate LNCaP cells activates its receptor (CXCR3) expression and inhibits cell proliferation
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Sarcoidosis and NOD1 variation with impaired recognition of intracellular Propionibacterium acnes
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Rapid pacing of embryoid bodies impairs mitochondrial ATP synthesis by a calcium-dependent mechanism—A model of in vitro differentiated cardiomyocytes to study molecular effects of tachycardia
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The role of PDE4 in pulmonary inflammation and goblet cell hyperplasia in allergic rats
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GAPDH as a sensor of NO stress
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A missense mutation (c.184C > T) in ovine CLN6 causes neuronal ceroid lipofuscinosis in Merino sheep whereas affected South Hampshire sheep have reduced levels of CLN6 mRNA
Fulltext Access 8 Pages 2006
Neuronal ceroid lipofuscinosis in Devon cattle is caused by a single base duplication (c.662dupG) in the bovine CLN5 gene
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Diagnosis of the neuronal ceroid lipofuscinoses: An update
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Molecular genetics of the NCLs — status and perspectives
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Functional properties of two mutants of human glucose 6-phosphate dehydrogenase, R393G and R393H, corresponding to the clinical variants G6PD Wisconsin and Nashville
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Evidence for a protective role for adiponectin in osteoarthritis
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Increased levels of F2-isoprostanes following aneurysmal subarachnoid hemorrhage in humans
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The measurement of blood and plasma nitrite by chemiluminescence: Pitfalls and solutions
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Premature cellular senescence induced by pyocyanin, a redox-active Pseudomonas aeruginosa toxin
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Metabolic capacity regulates iron homeostasis in endothelial cells
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Tumor macrophage redox and effector mechanisms associated with hypoxia
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Cytotoxic and mutagenic effects of tobacco-borne free fatty acids
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Differential oxidation of thioredoxin-1, thioredoxin-2, and glutathione by metal ions*
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Hydrogen peroxide causes uncoupling of dopamine D1-like receptors from G proteins via a mechanism involving protein kinase C and G-protein-coupled receptor kinase 2
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Synergistic protection by S-adenosylmethionine with vitamins C and E on liver injury induced by thioacetamide in rats
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The oxidation of 2′,7′-dichlorofluorescin to reactive oxygen species: A self-fulfilling prophesy?
Fulltext Access 8 Pages 2006
Biliverdin reductase, a major physiologic cytoprotectant, suppresses experimental autoimmune encephalomyelitis
Fulltext Access 8 Pages 2006
Moderate hypoxia induces xanthine oxidoreductase activity in arterial endothelial cells
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Alcohol consumption is directly associated with circulating oxidized low-density lipoprotein
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The epidemiology of ALS and the role of population-based registries
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Mechanisms of nitric-oxide-induced increase of free cytosolic Ca2+ concentration in Nicotiana plumbaginifolia cells
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Carbon monoxide, oxidative stress, and mitochondrial permeability pore transition
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Ultraviolet A sensitivity in Smith–Lemli–Opitz syndrome: Possible involvement of cholesta-5,7,9(11)-trien-3β-ol
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Potent antiproliferative effects of resveratrol on human osteosarcoma SJSA1 cells: novel cellular mechanisms involving the ERKs/p53 cascade
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Long-term moderate magnesium-deficient diet shows relationships between blood pressure, inflammation and oxidant stress defense in aging rats
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Mitochondrial defects and oxidative damage in patients with peripheral arterial disease
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Diabetes, glucose toxicity, and oxidative stress: A case of double jeopardy for the pancreatic islet β cell
Fulltext Access 8 Pages 2006
Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions
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The acute-phase response of the liver in relation to thyroid hormone-induced redox signaling
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Occurrence of trans fatty acids in rats fed a trans-free diet: A free radical-mediated formation?
Fulltext Access 8 Pages 2006
Vitamin C fails to protect amino acids and lipids from oxidation during acute inflammation
Fulltext Access 8 Pages 2006
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