Solution Structure of the C-terminal Dimerization Domain of SARS Coronavirus Nucleocapsid Protein Solved by the SAIL-NMR Method Fulltext Access 15 Pages 2008
Experimental and Computational Analyses of the Energetic Basis for Dual Recognition of Immunity Proteins by Colicin Endonucleases Fulltext Access 15 Pages 2008
Effect of Lipid Composition on the Topography of Membrane-Associated Hydrophobic Helices: Stabilization of Transmembrane Topography by Anionic Lipids Fulltext Access 15 Pages 2008
Sequence and Structural Determinants of Strand Swapping in Cadherin Domains: Do All Cadherins Bind Through the Same Adhesive Interface? Fulltext Access 15 Pages 2008
Tet Repressor Induction by Tetracycline: A Molecular Dynamics, Continuum Electrostatics, and Crystallographic Study Fulltext Access 15 Pages 2008
Crystal Structure of Lsm3 Octamer from Saccharomyces cerevisiae: Implications for Lsm Ring Organisation and Recruitment Fulltext Access 15 Pages 2008
Isolation of an Isoenzyme of Human Glutaminyl Cyclase: Retention in the Golgi Complex Suggests Involvement in the Protein Maturation Machinery Fulltext Access 15 Pages 2008
Backrub-Like Backbone Simulation Recapitulates Natural Protein Conformational Variability and Improves Mutant Side-Chain Prediction Fulltext Access 15 Pages 2008
Structures and Free-Energy Landscapes of the Wild Type and Mutants of the Aβ21–30 Peptide Are Determined by an Interplay between Intrapeptide Electrostatic and Hydrophobic Interactions Fulltext Access 15 Pages 2008
Different Requirements of the Kinase and UHM Domains of KIS for Its Nuclear Localization and Binding to Splicing Factors Fulltext Access 15 Pages 2008
Restriction Endonuclease Inhibitor IPI* of Bacteriophage T4: A Novel Structure for a Dedicated Target Fulltext Access 15 Pages 2008
Identification of Intrinsic Dynamics in a DNA Sequence Preferentially Cleaved by Topoisomerase II Enzyme Fulltext Access 15 Pages 2008
Structural and Energetic Analysis of Activation by a Cyclic Nucleotide Binding Domain Fulltext Access 15 Pages 2008
Calorimetric and Spectroscopic Studies of Hoechst 33258: Self-association and Binding to Non-cognate DNA Fulltext Access 15 Pages 2008
Crystal Structures of Multiple GATA Zinc Fingers Bound to DNA Reveal New Insights into DNA Recognition and Self-Association by GATA Fulltext Access 15 Pages 2008
Picomolar Affinity Fibronectin Domains Engineered Utilizing Loop Length Diversity, Recursive Mutagenesis, and Loop Shuffling Fulltext Access 15 Pages 2008
A Molecular Dynamics Study of the Interaction of d-Peptide Amyloid Inhibitors with Their Target Sequence Reveals a Potential Inhibitory Pharmacophore Conformation Fulltext Access 15 Pages 2008
Membrane Structure of CtrA3, a Copper-transporting P-type-ATPase from Aquifex aeolicus Fulltext Access 15 Pages 2008
Stabilization of the Human β2-Adrenergic Receptor TM4–TM3–TM5 Helix Interface by Mutagenesis of Glu1223.41, A Critical Residue in GPCR Structure Fulltext Access 15 Pages 2008
Amino Acid Starvation and Colicin D Treatment Induce A-site mRNA Cleavage in Escherichia coli Fulltext Access 15 Pages 2008
Directed Evolution to Low Nanomolar Affinity of a Tumor-Targeting Epidermal Growth Factor Receptor-Binding Affibody Molecule Fulltext Access 15 Pages 2008
Interaction with 7SL RNA but Not with HIV-1 Genomic RNA or P Bodies Is Required for APOBEC3F Virion Packaging Fulltext Access 15 Pages 2008
Sequential Barriers and an Obligatory Metastable Intermediate Define the Apparent Two-state Folding Pathway of the Ubiquitin-like PB1 Domain of NBR1 Fulltext Access 15 Pages 2008
Bioactivity of Folding Intermediates Studied by the Recovery of Enzymatic Activity during Refolding Fulltext Access 15 Pages 2008
Fast Fluorescence Laser Tracking Microrheometry, II: Quantitative Studies of Cytoskeletal Mechanotransduction Fulltext Access 15 Pages 2008
Novel Structural and Functional Mode of a Knot Essential for RNA Binding Activity of the Esa1 Presumed Chromodomain Fulltext Access 15 Pages 2008
Induction and Relaxation Dynamics of the Regulatory Network Controlling the Type III Secretion System Encoded within Salmonella Pathogenicity Island 1 Fulltext Access 15 Pages 2008
Structural Determinants of Glutathione Transferases with Azathioprine Activity Identified by DNA Shuffling of Alpha Class Members Fulltext Access 15 Pages 2008
Structural Role of Bacterioruberin in the Trimeric Structure of Archaerhodopsin-2 Fulltext Access 15 Pages 2008
Mechanistic Insights into the Role of Val75 of HIV-1 Reverse Transcriptase in Misinsertion and Mispair Extension Fidelity of DNA Synthesis Fulltext Access 15 Pages 2008
Structure and Function of the Arginine Repressor-Operator Complex from Bacillus subtilis Fulltext Access 15 Pages 2008
Structural Enzymological Studies of 2-Enoyl Thioester Reductase of the Human Mitochondrial FAS II Pathway: New Insights into Its Substrate Recognition Properties Fulltext Access 15 Pages 2008
Structure of the Leech Protein Saratin and Characterization of Its Binding to Collagen Fulltext Access 15 Pages 2008
The Polybasic N-Terminal Region of the Prion Protein Controls the Physical Properties of Both the Cellular and Fibrillar Forms of PrP Fulltext Access 15 Pages 2008
The Structure and Unusual Protein Chemistry of Hypoxic Response Protein 1, a Latency Antigen and Highly Expressed Member of the DosR Regulon in Mycobacterium tuberculosis Fulltext Access 15 Pages 2008
Solution NMR Structure of Putidaredoxin–Cytochrome P450cam Complex via a Combined Residual Dipolar Coupling–Spin Labeling Approach Suggests a Role for Trp106 of Putidaredoxin in Complex Formation Fulltext Access 15 Pages 2008
Thermodynamics, Kinetics, and Salt dependence of Folding of YopM, a Large Leucine-rich Repeat Protein Fulltext Access 15 Pages 2008
Solution Structure and Characterization of the DNA-Binding Activity of the B3BP–Smr Domain Fulltext Access 15 Pages 2008
Stability and ATP Binding of the Nucleotide-binding Domain of the Wilson Disease Protein: Effect of the Common H1069Q Mutation Fulltext Access 15 Pages 2008
Mechanistic Basis of Zidovudine Hypersusceptibility and Lamivudine Resistance Conferred by the Deletion of Codon 69 in the HIV-1 Reverse Transcriptase Coding Region Fulltext Access 15 Pages 2008
Combinatorial Optimization of a CD4-Mimetic Miniprotein and Cocrystal Structures with HIV-1 gp120 Envelope Glycoprotein Fulltext Access 15 Pages 2008
Crystallographic Structure of Phosphofructokinase-2 from Escherichia coli in Complex with Two ATP Molecules. Implications for Substrate Inhibition Fulltext Access 15 Pages 2008
Crystal Structure of the Escherichia coli 23S rRNA:m5C Methyltransferase RlmI (YccW) Reveals Evolutionary Links between RNA Modification Enzymes Fulltext Access 15 Pages 2008
Biochemical and Structural Characterization of a Novel Family of Cystathionine β-Synthase Domain Proteins Fused to a Zn Ribbon-Like Domain Fulltext Access 15 Pages 2008
A Contact Photo-Cross-linking Investigation of the Active Site of the 8-17 Deoxyribozyme Fulltext Access 15 Pages 2008
Complex of a Protective Antibody with Its Ebola Virus GP Peptide Epitope: Unusual Features of a Vλx Light Chain Fulltext Access 15 Pages 2008
Structure of the Yeast SR Protein Npl3 and Interaction with mRNA 3′-End Processing Signals Fulltext Access 15 Pages 2008
New Insights into Multiple Coagulation Factor Deficiency from the Solution Structure of Human MCFD2 Fulltext Access 15 Pages 2008
A New Model for Growth Factor Activation: Type II Receptors Compete with the Prodomain for BMP-7 Fulltext Access 15 Pages 2008
Changing the Determinants of Protein Stability from Covalent to Non-Covalent Interactions by In Vitro Evolution: A Structural and Energetic Analysis Fulltext Access 15 Pages 2008
Specific Interdomain Synergy in the UapA Transporter Determines Its Unique Specificity for Uric Acid among NAT Carriers Fulltext Access 15 Pages 2008
Sensitive Genome-Wide Screen for Low Secondary Enzymatic Activities: The YjbQ Family Shows Thiamin Phosphate Synthase Activity Fulltext Access 15 Pages 2008
Transfer of Flexibility between Ankyrin Repeats in IκBα upon Formation of the NF-κB Complex Fulltext Access 15 Pages 2008
Structural Basis for the Interaction between the Cytoplasmic Domain of the Hyaluronate Receptor Layilin and the Talin F3 Subdomain Fulltext Access 15 Pages 2008
Engineering Variants of the I-SceI Homing Endonuclease with Strand-specific and Site-specific DNA-nicking Activity Fulltext Access 15 Pages 2008
Hindered Diffusion through an Aqueous Pore Describes Invariant Dye Selectivity of Cx43 Junctions Fulltext Access 15 Pages 2008
Functional Characterization of the Escherichia coli Fis–DNA Binding Sequence Fulltext Access 15 Pages 2008
Ultrastructural matrix-mineral relationships in avian eggshell, and effects of osteopontin on calcite growth in vitro Fulltext Access 16 Pages 2008
Reprint of “On the feasibility of visualizing ultrasmall gold labels in biological specimens by STEM tomography” [J. Struct. Biol. 159 (2007) 507-522] Fulltext Access 16 Pages 2008
Quantitative Aspects of and Ionization Mechanisms in Positive-Ion Atmospheric Pressure Chemical Ionization Mass Spectrometry Fulltext Access 16 Pages 2008
Expedited approaches to whole cell electron tomography and organelle mark-up in situ in high-pressure frozen pancreatic islets Fulltext Access 16 Pages 2008
Markov random field based automatic image alignment for electron tomography Fulltext Access 16 Pages 2008
Bioorganic/inorganic hybrid composition of sponge spicules: Matrix of the giant spicules and of the comitalia of the deep sea hexactinellid Monorhaphis Fulltext Access 16 Pages 2008
Structural features of the single-stranded DNA-binding protein of Epstein–Barr virus Fulltext Access 16 Pages 2008
Structure of B-MLV Capsid Amino-terminal Domain Reveals Key Features of Viral Tropism, Gag Assembly and Core Formation Fulltext Access 16 Pages 2008
The Crystal Structure of β-Alanine Synthase from Drosophila melanogaster Reveals a Homooctameric Helical Turn-Like Assembly Fulltext Access 16 Pages 2008
Energetic Coupling Between Native-State Prolyl Isomerization and Conformational Protein Folding Fulltext Access 16 Pages 2008
Protein–DNA Interactions That Govern AAA+ Activator-Dependent Bacterial Transcription Initiation Fulltext Access 16 Pages 2008
Modulating Catalytic Activity by Unnatural Amino Acid Residues in a GSH-Binding Loop of GST P1-1 Fulltext Access 16 Pages 2008
Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1 Fulltext Access 16 Pages 2008
Bax- or Bak-Induced Mitochondrial Fission Can Be Uncoupled from Cytochrome c Release Fulltext Access 16 Pages 2008
Structural Details of HIV-1 Recognition by the Broadly Neutralizing Monoclonal Antibody 2F5: Epitope Conformation, Antigen-Recognition Loop Mobility, and Anion-Binding Site Fulltext Access 16 Pages 2008
Allophycocyanin Trimer Stability and Functionality Are Primarily Due to Polar Enhanced Hydrophobicity of the Phycocyanobilin Binding Pocket Fulltext Access 16 Pages 2008
Zinc Binding Modulates the Entire Folding Free Energy Surface of Human Cu,Zn Superoxide Dismutase Fulltext Access 16 Pages 2008
A DExH/D-box Protein Coordinates the Two Steps of Splicing in a Group I Intron Fulltext Access 16 Pages 2008
Dissecting NGF Interactions with TrkA and p75 Receptors by Structural and Functional Studies of an Anti-NGF Neutralizing Antibody Fulltext Access 16 Pages 2008
The Molecular Structure of Epoxide Hydrolase B from Mycobacterium tuberculosis and Its Complex with a Urea-Based Inhibitor Fulltext Access 16 Pages 2008
IL-22R, IL-10R2, and IL-22BP Binding Sites Are Topologically Juxtaposed on Adjacent and Overlapping Surfaces of IL-22 Fulltext Access 16 Pages 2008
GAPDH Is Conformationally and Functionally Altered in Association with Oxidative Stress in Mouse Models of Amyotrophic Lateral Sclerosis Fulltext Access 16 Pages 2008
Crystal Structure of Metastasis-Associated Protein S100A4 in the Active Calcium-Bound Form Fulltext Access 16 Pages 2008
Three-Layer ONIOM Studies of the Dark State of Rhodopsin: The Protonation State of Glu181 Fulltext Access 16 Pages 2008
Structural Basis of the LOV1 Dimerization of Arabidopsis Phototropins 1 and 2 Fulltext Access 16 Pages 2008
Folding of the KIX Domain: Characterization of the Equilibrium Analog of a Folding Intermediate using 15N/13C Relaxation Dispersion and Fast 1H/2H Amide Exchange NMR Spectroscopy Fulltext Access 16 Pages 2008
Crystal Structure and Raman Studies of dsFP483, a Cyan Fluorescent Protein from Discosoma striata Fulltext Access 16 Pages 2008
Molecular Dynamics—Solvated Interaction Energy Studies of Protein–Protein Interactions: The MP1–p14 Scaffolding Complex Fulltext Access 16 Pages 2008
The in Vivo and in Vitro Aggregation Properties of Globular Proteins Correlate With Their Conformational Stability: The SH3 Case Fulltext Access 16 Pages 2008
Structure of the Yersinia enterocolitica Type III Secretion Translocator Chaperone SycD Fulltext Access 16 Pages 2008
The Neuralized Homology Repeat 1 Domain of Drosophila Neuralized Mediates Nuclear Envelope Association and Delta-dependent Inhibition of Nuclear Import Fulltext Access 16 Pages 2008