The Central Cavity from the (Alpha/Alpha)6 Barrel Structure of Anabaena sp. CH1 N-Acetyl-d-glucosamine 2-Epimerase Contains Two Key Histidine Residues for Reversible Conversion Fulltext Access 14 Pages 2007
A Designed Ankyrin Repeat Protein Evolved to Picomolar Affinity to Her2 Fulltext Access 14 Pages 2007
Thioaptamer Interactions with Prion Proteins: Sequence-specific and Non-specific Binding Sites Fulltext Access 14 Pages 2007
A DNA-translocating Snf2 Molecular Motor: Saccharomyces cerevisiae Rdh54 Displays Processive Translocation and Extrudes DNA Loops Fulltext Access 14 Pages 2007
Structural Insights into the Second Step of RNA-dependent Cysteine Biosynthesis in Archaea: Crystal Structure of Sep-tRNA:Cys-tRNA Synthase from Archaeoglobus fulgidus Fulltext Access 14 Pages 2007
Crystal Structures of two Bordetella pertussis Periplasmic Receptors Contribute to Defining a Novel Pyroglutamic Acid Binding DctP Subfamily Fulltext Access 14 Pages 2007
Structure of the Cytochrome b6f Complex: Quinone Analogue Inhibitors as Ligands of Heme cn Fulltext Access 14 Pages 2007
DEAD-box-protein-assisted RNA Structure Conversion Towards and Against Thermodynamic Equilibrium Values Fulltext Access 14 Pages 2007
The Structure of the Regulatory Domain of the Adenylyl Cyclase Rv1264 from Mycobacterium tuberculosis with Bound Oleic Acid Fulltext Access 14 Pages 2007
Dynamic Structural Rearrangements Between DNA Binding Modes of E. coli SSB Protein Fulltext Access 14 Pages 2007
Inhibition of the Activities of Reverse Transcriptase and Integrase of Human Immunodeficiency Virus Type-1 by Peptides Derived from the Homologous Viral Protein R (Vpr) Fulltext Access 14 Pages 2007
Modelling Transcriptional Interference and DNA Looping in Gene Regulation Fulltext Access 14 Pages 2007
Substrate and Product Complexes of Escherichia coli Adenylosuccinate Lyase Provide New Insights into the Enzymatic Mechanism Fulltext Access 14 Pages 2007
The Identification of Similarities between Biological Networks: Application to the Metabolome and Interactome Fulltext Access 14 Pages 2007
The Three-dimensional Structure of N-Succinyldiaminopimelate Aminotransferase from Mycobacterium tuberculosis Fulltext Access 14 Pages 2007
NMR Structure and Functional Characterization of a Human Cancer-related Nucleoside Triphosphatase Fulltext Access 14 Pages 2007
Distinct Effector-binding Sites Enable Synergistic Transcriptional Activation by BenM, a LysR-type Regulator Fulltext Access 14 Pages 2007
Structural Insight into a Molecular Switch in Tandem Winged-helix Motifs from Elongation Factor SelB Fulltext Access 14 Pages 2007
Structural Characterization of the Tetrameric form of the Major Cat Allergen Fel d 1 Fulltext Access 14 Pages 2007
Differential Effects of Phosphorylation on DNA Binding Properties of N Oct-3 Are Dictated by Protein/DNA Complex Structures Fulltext Access 14 Pages 2007
Assembly of the Small Outer Capsid Protein, Soc, on Bacteriophage T4: A Novel System for High Density Display of Multiple Large Anthrax Toxins and Foreign Proteins on Phage Capsid Fulltext Access 14 Pages 2007
The Rate of TRAP Binding to RNA Is Crucial for Transcription Attenuation Control of the B. subtilis trp Operon Fulltext Access 14 Pages 2007
Conservation and Diversity Among the Three-dimensional Folds of the Dicistroviridae Intergenic Region IRESes Fulltext Access 14 Pages 2007
Structures of Ligand-free and Inhibitor Complexes of Dihydroorotase from Escherichia coli: Implications for Loop Movement in Inhibitor Design Fulltext Access 14 Pages 2007
Searching for Multiple Folding Pathways of a Nearly Symmetrical Protein: Temperature Dependent Φ-Value Analysis of the B Domain of Protein A Fulltext Access 14 Pages 2007
Structure of the Escherichia coli Leucine-responsive Regulatory Protein Lrp Reveals a Novel Octameric Assembly Fulltext Access 14 Pages 2007
Protonated Nitro Group as a Gas-Phase Electrophile: Experimental and Theoretical Study of the Cyclization of o-Nitrodiphenyl Ethers, Amines, and Sulfides Fulltext Access 14 Pages 2007
Hydroxyl Groups in the ββ Sandwich of Metallo-β-lactamases Favor Enzyme Activity: Tyr218 and Ser262 Pull Down the Lid Fulltext Access 14 Pages 2007
Rigidification of a Flexible Protease Inhibitor Variant upon Binding to Trypsin Fulltext Access 14 Pages 2007
The Crystal Structures of Human Calpains 1 and 9 Imply Diverse Mechanisms of Action and Auto-inhibition Fulltext Access 14 Pages 2007
Solution Structure and Backbone Dynamics of the Reduced Form and an Oxidized Form of E. coli Methionine Sulfoxide Reductase A (MsrA): Structural Insight of the MsrA Catalytic Cycle Fulltext Access 14 Pages 2007
Dodecameric Structure and ATPase Activity of the Human TIP48/TIP49 Complex Fulltext Access 14 Pages 2007
The Structure of the Minimal Relaxase Domain of MobA at 2.1 Å Resolution Fulltext Access 14 Pages 2007
Exploiting Elements of Transcriptional Machinery to Enhance Protein Stability Fulltext Access 14 Pages 2007
Saccharomyces cerevisiae MSH2–MSH3 and MSH2–MSH6 Complexes Display Distinct Requirements for DNA Binding Domain I in Mismatch Recognition Fulltext Access 14 Pages 2007
Ubiquitin-dependent Proteolysis of the Microtubule End-binding Protein 1, EB1, Is Controlled by the COP9 Signalosome: Possible Consequences for Microtubule Filament Stability Fulltext Access 14 Pages 2007
Structural Analysis of a Ternary Complex of Allantoate Amidohydrolase from Escherichia coli Reveals its Mechanics Fulltext Access 14 Pages 2007
The Structure of the KinA-Sda Complex Suggests an Allosteric Mechanism of Histidine Kinase Inhibition Fulltext Access 14 Pages 2007
Affilin–Novel Binding Molecules Based on Human γ-B-Crystallin, an All β-Sheet Protein Fulltext Access 14 Pages 2007
Examination of the Long-range Effects of Aminofluorene-induced Conformational Heterogeneity and Its Relevance to the Mechanism of Translesional DNA Synthesis Fulltext Access 14 Pages 2007
Structural Studies of the Alzheimer’s Amyloid Precursor Protein Copper-binding Domain Reveal How it Binds Copper Ions Fulltext Access 14 Pages 2007
Novel Families of Toxin-like Peptides in Insects and Mammals: A Computational Approach Fulltext Access 14 Pages 2007
Crystal Structure of the Cofactor-Binding Domain of the Human Phase II Drug-Metabolism Enzyme UDP-Glucuronosyltransferase 2B7 Fulltext Access 14 Pages 2007
Mapping Putative Contact Sites Between Subunits in a Bacterial ATP-binding Cassette (ABC) Transporter by Synthetic Peptide Libraries Fulltext Access 14 Pages 2007
Insights into Molecular Plasticity of Choline Binding Proteins (Pneumococcal Surface Proteins) by SAXS Fulltext Access 14 Pages 2007
Plasmid-encoded Antirestriction Protein ArdA Can Discriminate between Type I Methyltransferase and Complete Restriction–Modification System Fulltext Access 14 Pages 2007
Hydrophobic Surface Burial Is the Major Stability Determinant of a Flat, Single-layer β-Sheet Fulltext Access 14 Pages 2007
Structural Studies of E. coli Topoisomerase III-DNA Complexes Reveal a Novel Type IA Topoisomerase-DNA Conformational Intermediate Fulltext Access 14 Pages 2007
Crosslinking of Translation Factor EF-G to Proteins of the Bacterial Ribosome Before and After Translocation Fulltext Access 14 Pages 2007
The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation Fulltext Access 14 Pages 2007
Sodium Channels: Ionic Model of Slow Inactivation and State-Dependent Drug Binding Fulltext Access 14 Pages 2007
Structural and Functional Analysis of Methylation and 5′-RNA Sequence Requirements of Short Capped RNAs by the Methyltransferase Domain of Dengue Virus NS5 Fulltext Access 14 Pages 2007
TFIIA Changes the Conformation of the DNA in TBP/TATA Complexes and Increases their Kinetic Stability Fulltext Access 14 Pages 2007
Cellular Remodelling of Individual Collagen Fibrils Visualized by Time-lapse AFM Fulltext Access 14 Pages 2007
Structures of MART-126/27–35 Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition Fulltext Access 14 Pages 2007
Structural Characterization of Zinc-deficient Human Superoxide Dismutase and Implications for ALS Fulltext Access 14 Pages 2007
Electrostatic Contributions to the Stability of the GCN4 Leucine Zipper Structure Fulltext Access 14 Pages 2007
Identification of Rare Slipknots in Proteins and Their Implications for Stability and Folding Fulltext Access 14 Pages 2007
p66 Trp24 and Phe61 Are Essential for Accurate Association of HIV-1 Reverse Transcriptase with Primer/Template Fulltext Access 14 Pages 2007
Dynamics of a Benzo[a]pyrene-derived Guanine DNA Lesion in TGT and CGC Sequence Contexts: Enhanced Mobility in TGT Explains Conformational Heterogeneity, Flexible Bending, and Greater Susceptibility to Nucleotide Excision Repair Fulltext Access 14 Pages 2007
Bending Dynamics of Fluctuating Biopolymers Probed by Automated High-Resolution Filament Tracking Fulltext Access 14 Pages 2007
Binding of Lysozyme to Phospholipid Bilayers: Evidence for Protein Aggregation upon Membrane Association Fulltext Access 14 Pages 2007
Crystal Structure of the Stationary Phase Survival Protein SurE with Metal Ion and AMP Fulltext Access 14 Pages 2007
Translational regulation of PGHS-1 mRNA: 5′ untranslated region and first two exons conferring negative regulation Fulltext Access 14 Pages 2007
Plant SET domain-containing proteins: Structure, function and regulation Fulltext Access 14 Pages 2007
Immunohistochemical study of the reticular and vascular network of mouse lymph node using vibratome sections Fulltext Access 14 Pages 2007
Palatal fusion – Where do the midline cells go?: A review on cleft palate, a major human birth defect Fulltext Access 14 Pages 2007
Developing Limited Proteolysis and Mass Spectrometry for the Characterization of Ribosome Topography Fulltext Access 14 Pages 2007
A Glycomics Platform for the Analysis of Permethylated Oligosaccharide Alditols Fulltext Access 14 Pages 2007
Gas-Phase Stability of G-quadruplex DNA Determined by Electrospray Ionization Tandem Mass Spectrometry and Molecular Dynamics Simulations Fulltext Access 14 Pages 2007
Bimolecular and Unimolecular Contributions to the Disparate Self-Chemical Ionizations of α-Pinene and Camphene Isomers Fulltext Access 14 Pages 2007
Factors That Impact the Vacuum Ultraviolet Photofragmentation of Peptide Ions Fulltext Access 14 Pages 2007
Structural Characterization of Phosphatidyl-myo-Inositol Mannosides from Mycobacterium bovis Bacillus Calmette Gúerin by Multiple-Stage Quadrupole Ion-Trap Mass Spectrometry with Electrospray Ionization. II. Monoacyl- and Diacyl-PIMs Fulltext Access 14 Pages 2007
A Novel Roll-and-Slide Mechanism of DNA Folding in Chromatin: Implications for Nucleosome Positioning Fulltext Access 14 Pages 2007
Structural Metals in the Group I Intron: A Ribozyme with a Multiple Metal Ion Core Fulltext Access 14 Pages 2007
In vitro Reconstitution and Characterization of the Yeast Mitochondrial Degradosome Complex Unravels Tight Functional Interdependence Fulltext Access 14 Pages 2007
Jab1 Mediates Protein Degradation of the Rad9-Rad1-Hus1 Checkpoint Complex Fulltext Access 14 Pages 2007
pH Modulates the Quinone Position in the Photosynthetic Reaction Center from Rhodobacter sphaeroides in the Neutral and Charge Separated States Fulltext Access 14 Pages 2007
Domain Organization and Polarity of Tail Needle GP26 in the Portal Vertex Structure of Bacteriophage P22 Fulltext Access 14 Pages 2007
Photochemical Intermediates of Arabidopsis Phototropin 2 LOV Domains Associated with Conformational Changes Fulltext Access 14 Pages 2007
Association of Dystrobrevin and Regulatory Subunit of Protein Kinase A: A New Role for Dystrobrevin as a Scaffold for Signaling Proteins Fulltext Access 14 Pages 2007
NMR analysis of [methyl-13C]methionine UvrB from Bacillus caldotenax reveals UvrB–domain 4 heterodimer formation in solution Fulltext Access 14 Pages 2007
Bipolar, Dual Plasmodium falciparum Helicase 45 Expressed in the Intraerythrocytic Developmental Cycle Is Required for Parasite Growth Fulltext Access 14 Pages 2007
The Structures of Bacteriophages K1E and K1-5 Explain Processive Degradation of Polysaccharide Capsules and Evolution of New Host Specificities Fulltext Access 14 Pages 2007
Formation of (bn−1 + H2O) Ions by Collisional Activation of MALDI-Formed Peptide [M + H]+ Ions in a QqTOF Mass Spectrometer Fulltext Access 14 Pages 2007
Probing the Flexibility of the DsbA Oxidoreductase from Vibrio cholerae—a 15N - 1H Heteronuclear NMR Relaxation Analysis of Oxidized and Reduced Forms of DsbA Fulltext Access 14 Pages 2007
The C2 Domains of Classical PKCs are Specific PtdIns(4,5)P2-sensing Domains with Different Affinities for Membrane Binding Fulltext Access 14 Pages 2007
CTL Recognition of a Protective Immunodominant Influenza A Virus Nucleoprotein Epitope Utilizes a Highly Restricted Vβ but Diverse Vα Repertoire: Functional and Structural Implications Fulltext Access 14 Pages 2007
The 73 kDa Subunit of the CPSF Complex Binds to the HIV-1 LTR Promoter and Functions as a Negative Regulatory Factor that Is Inhibited by the HIV-1 Tat Protein Fulltext Access 14 Pages 2007
Specific Interaction between EF-G and RRF and Its Implication for GTP-Dependent Ribosome Splitting into Subunits Fulltext Access 14 Pages 2007
Crystal Structure of the Ligand-Binding Protein EhuB from Sinorhizobium meliloti Reveals Substrate Recognition of the Compatible Solutes Ectoine and Hydroxyectoine Fulltext Access 14 Pages 2007
Predicting Knot or Catenane Type of Site-Specific Recombination Products Fulltext Access 14 Pages 2007
The Heterodimeric Primase from the Euryarchaeon Pyrococcus abyssi: A Multifunctional Enzyme for Initiation and Repair? Fulltext Access 14 Pages 2007
The Nucleoside Triphosphate Diphosphohydrolase-1/CD39 Is Incorporated into Human Immunodeficiency Type 1 Particles, Where It Remains Biologically Active Fulltext Access 14 Pages 2007