Mapping the Folding Free Energy Surface for Metal-free Human Cu,Zn Superoxide Dismutase Fulltext Access 19 Pages 2006
In Meso Structure of the Cobalamin Transporter, BtuB, at 1.95 Å Resolution Fulltext Access 19 Pages 2006
Binding-induced Stabilization and Assembly of the Phage P22 Tail Accessory Factor Gp4 Fulltext Access 19 Pages 2006
X-ray Interference Studies of Crossbridge Action in Muscle Contraction: Evidence from Quick Releases Fulltext Access 19 Pages 2006
Kinetics of Insulin-like Growth Factor II (IGF-II) Interaction with Domain 11 of the Human IGF-II/Mannose 6-phosphate Receptor: Function of CD and AB Loop Solvent-exposed Residues Fulltext Access 19 Pages 2006
Structure of the Sulfolobus solfataricus α-Glucosidase: Implications for Domain Conservation and Substrate Recognition in GH31 Fulltext Access 19 Pages 2006
Heterotetrameric Sarcosine Oxidase: Structure of a Diflavin Metalloenzyme at 1.85 Å Resolution Fulltext Access 19 Pages 2006
Crystal Structure of 3-Hydroxybenzoate Hydroxylase from Comamonas testosteroni Has a Large Tunnel for Substrate and Oxygen Access to the Active Site Fulltext Access 19 Pages 2006
Toward an Accurate Theoretical Framework for Describing Ensembles for Proteins under Strongly Denaturing Conditions Fulltext Access 19 Pages 2006
Enhancing the acquisition efficiency of fast magnetic resonance imaging via broadband encoding of signal content Fulltext Access 19 Pages 2006
Identification of a Collapsed Intermediate with Non-native Long-range Interactions on the Folding Pathway of a Pair of Fyn SH3 Domain Mutants by NMR Relaxation Dispersion Spectroscopy Fulltext Access 19 Pages 2006
SRY-directed DNA Bending and Human Sex Reversal: Reassessment of a Clinical Mutation Uncovers a Global Coupling between the HMG Box and its Tail Fulltext Access 19 Pages 2006
Dynamics of Allostery in Hemoglobin: Roles of the Penultimate Tyrosine H bonds Fulltext Access 19 Pages 2006
Structural Bases of Feed-back Control of Arginine Biosynthesis, Revealed by the Structures of Two Hexameric N-Acetylglutamate Kinases, from Thermotoga maritima and Pseudomonas aeruginosa Fulltext Access 19 Pages 2006
Inhibition of Papillomavirus Protein Function in Cervical Cancer Cells by Intrabody Targeting Fulltext Access 19 Pages 2006
Structural and Biochemical Study of Effector Molecule Recognition by the E. coli Glyoxylate and Allantoin Utilization Regulatory Protein AllR Fulltext Access 19 Pages 2006
Purification, Properties and Extended Solution Structure of the Complex Formed between Human Immunoglobulin A1 and Human Serum Albumin by Scattering and Ultracentrifugation Fulltext Access 19 Pages 2006
Searching for silver bullets: An alternative strategy for crystallizing macromolecules Fulltext Access 20 Pages 2006
Structural Basis of Carbohydrate Transfer Activity by Human UDP-GalNAc: Polypeptide α-N-Acetylgalactosaminyltransferase (pp-GalNAc-T10) Fulltext Access 20 Pages 2006
A Consistent Model for Thermal Fluctuations and Protein-Induced Deformations in Lipid Bilayers Fulltext Access 20 Pages 2006
Probing the Mechanism of Amyloidogenesis through a Tandem Repeat of the PI3-SH3 Domain Suggests a Generic Model for Protein Aggregation and Fibril Formation Fulltext Access 20 Pages 2006
A Structural Model for the Large Subunit of the Mammalian Mitochondrial Ribosome Fulltext Access 20 Pages 2006
How Proteins Trigger Excitation Energy Transfer in the FMO Complex of Green Sulfur Bacteria Fulltext Access 20 Pages 2006
Multiple U2AF65 Binding Sites within SF3b155: Thermodynamic and Spectroscopic Characterization of Protein–Protein Interactions among pre-mRNA Splicing Factors Fulltext Access 20 Pages 2006
Oligomerisation of the Developmental Regulator Proline Rich Homeodomain (PRH/Hex) is Mediated by a Novel Proline-rich Dimerisation Domain Fulltext Access 20 Pages 2006
Evolutionary Dynamics of Prokaryotic Transcriptional Regulatory Networks Fulltext Access 20 Pages 2006
Investigations into the millimeter and submillimeter-wave spectrum of perdeuterated methanol, CD3OD, in its ground and first excited torsional states Fulltext Access 20 Pages 2006
Gene Expression Profiling of Ovarian Tissues for Determination of Molecular Pathways Reflective of Tumorigenesis Fulltext Access 20 Pages 2006
The IINS, IR and DFT studies of hydrogen bonds in 6-Furfuryl and 6-Benzylaminopurines Fulltext Access 20 Pages 2006
A spectroscopic and computational study of stereochemistry in 2-hydroxymutilin Fulltext Access 20 Pages 2006
Reaction Diffusion Modeling of Calcium Dynamics with Realistic ER Geometry Fulltext Access 21 Pages 2006
Mis-translation of a Computationally Designed Protein Yields an Exceptionally Stable Homodimer: Implications for Protein Engineering and Evolution Fulltext Access 21 Pages 2006
SRY and Human Sex Determination: The Basic Tail of the HMG Box Functions as a Kinetic Clamp to Augment DNA Bending Fulltext Access 21 Pages 2006
Crystallographic and Pre-steady-state Kinetics Studies on Binding of NADH to Wild-type and Isoniazid-resistant Enoyl-ACP(CoA) Reductase Enzymes from Mycobacterium tuberculosis Fulltext Access 21 Pages 2006
Structural Motif-Based Homology Modeling of CYP27A1 and Site-Directed Mutational Analyses Affecting Vitamin D Hydroxylation Fulltext Access 21 Pages 2006
Free Energy Landscapes of RNA/RNA Complexes: With Applications to snRNA Complexes in Spliceosomes Fulltext Access 21 Pages 2006
Statistical Thermodynamics and Kinetics of DNA Multiplex Hybridization Reactions Fulltext Access 21 Pages 2006
Mapping the Energetics of Water–Protein and Water–Ligand Interactions with the “Natural” HINT Forcefield: Predictive Tools for Characterizing the Roles of Water in Biomolecules Fulltext Access 21 Pages 2006
Thermochemistry of organic and heteroorganic species. Part XIII. Structural aspects and thermochemical approach to isomerization and fragmentation of negative ions. Simple bond cleavage and hydrogen rearrangement processes Fulltext Access 21 Pages 2006
DNA Polymerase X From African Swine Fever Virus: Quantitative Analysis of the Enzyme–ssDNA Interactions and the Functional Structure of the Complex Fulltext Access 21 Pages 2006
From the Similarity Analysis of Protein Cavities to the Functional Classification of Protein Families Using Cavbase Fulltext Access 22 Pages 2006
Crystal Structures of Beryllium Fluoride-free and Beryllium Fluoride-bound CheY in Complex with the Conserved C-terminal Peptide of CheZ Reveal Dual Binding Modes Specific to CheY Conformation Fulltext Access 22 Pages 2006
Identification and Biochemical Characterization of a Eukaryotic-type Serine/Threonine Kinase and its Cognate Phosphatase in Streptococcus pyogenes: Their Biological Functions and Substrate Identification Fulltext Access 22 Pages 2006
Insights into Protein–Protein Interfaces using a Bayesian Network Prediction Method Fulltext Access 22 Pages 2006
Mechanism of Chromosome Compaction and Looping by the Escherichia coli Nucleoid Protein Fis Fulltext Access 22 Pages 2006
Modularity of the Transcriptional Response of Protein Complexes in Yeast Fulltext Access 22 Pages 2006
Computational Studies of Tryptophanyl-tRNA Synthetase: Activation of ATP by Induced-Fit Fulltext Access 22 Pages 2006
Ion Permeation through a Narrow Channel: Using Gramicidin to Ascertain All-Atom Molecular Dynamics Potential of Mean Force Methodology and Biomolecular Force Fields Fulltext Access 22 Pages 2006
Thermochemistry of organic, heteroorganic and inorganic species. XV. The enthalpies of formation for halogenides of main group elements Fulltext Access 22 Pages 2006
Plasticity of the Gene Functions for DNA Replication in the T4-like Phages Fulltext Access 23 Pages 2006
The Changing Face of Glucagon Fibrillation: Structural Polymorphism and Conformational Imprinting Fulltext Access 23 Pages 2006
Evolution of Structure and Function in the o-Succinylbenzoate Synthase/N-Acylamino Acid Racemase Family of the Enolase Superfamily Fulltext Access 23 Pages 2006
Elucidating Quantitative Stability/Flexibility Relationships Within Thioredoxin and its Fragments Using a Distance Constraint Model Fulltext Access 23 Pages 2006
Experimental and Computational Analysis of Translation Products in Apomyoglobin Expression Fulltext Access 23 Pages 2006
Analysis of Binding at a Single Spatially Localized Cluster of Binding Sites by Fluorescence Recovery after Photobleaching Fulltext Access 23 Pages 2006
Statistical Evaluation of Ion-Channel Gating Models Based on Distributions of Log-Likelihood Ratios Fulltext Access 23 Pages 2006
Minimalist Representations and the Importance of Nearest Neighbor Effects in Protein Folding Simulations Fulltext Access 23 Pages 2006
Directed Evolution of an Anti-prion Protein scFv Fragment to an Affinity of 1 pM and its Structural Interpretation Fulltext Access 23 Pages 2006
The Ubiquitin Domain Superfold: Structure-based Sequence Alignments and Characterization of Binding Epitopes Fulltext Access 24 Pages 2006
Transform-based backprojection for volume reconstruction of large format electron microscope tilt series Fulltext Access 24 Pages 2006
Dynamics of Muscle Glycogenolysis Modeled with pH Time Course Computation and pH-Dependent Reaction Equilibria and Enzyme Kinetics Fulltext Access 24 Pages 2006
High resolution infrared study of D2CO in the region of 1780–2400 cm−1: assignment and preliminary analysis Fulltext Access 24 Pages 2006
Simultaneous analysis of rovibrational and rotational data for the 41, 51, 61, 72, 81, 7191 and 92 states of HCOOH Fulltext Access 24 Pages 2006
A Quantitative Analysis of Cardiac Myocyte Relaxation: A Simulation Study Fulltext Access 26 Pages 2006
A Computational Model Integrating Electrophysiology, Contraction, and Mitochondrial Bioenergetics in the Ventricular Myocyte Fulltext Access 26 Pages 2006
The double Renner effect: A theoretical study of the MgNC/MgCN isomerization in the AË 2Î electronic state Fulltext Access 28 Pages 2006
Osteoarthritis: Cellular and molecular changes in degenerating cartilage Fulltext Access 29 Pages 2006
Evolutionary Genomics of the HAD Superfamily: Understanding the Structural Adaptations and Catalytic Diversity in a Superfamily of Phosphoesterases and Allied Enzymes Fulltext Access 32 Pages 2006
Hypercytolipidemia-induced cellular lipoapoptosis: Cytostructural and endometabolic basis of progressive organo-involution following expression of diabetes (db/db) and obese (ob/ob) mutation syndromes Fulltext Access 51 Pages 2006