Synthesis, SAR studies, and pharmacological evaluation of 3-anilino-4-(3-indolyl) maleimides with conformationally restricted structure as orally bioavailable PKCβ-selective inhibitors Fulltext Access 14 Pages 2006
Design, synthesis, and biological evaluation of combretastatin nitrogen-containing derivatives as inhibitors of tubulin assembly and vascular disrupting agents Fulltext Access 14 Pages 2006
Design, synthesis, and biological testing of potential heme-coordinating nitric oxide synthase inhibitors Fulltext Access 14 Pages 2006
New insights about HERG blockade obtained from protein modeling, potential energy mapping, and docking studies Fulltext Access 14 Pages 2006
Conformationally restrained carbazolone-containing α,γ-diketo acids as inhibitors of HIV integrase Fulltext Access 14 Pages 2006
Recent developments in the identification of novel oxazolidinone antibacterial agents Fulltext Access 14 Pages 2006
Linear and nonlinear QSAR study of N-hydroxy-2-[(phenylsulfonyl)amino]acetamide derivatives as matrix metalloproteinase inhibitors Fulltext Access 14 Pages 2006
Antagonists of the myelin-associated glycoprotein: A new class of tetrasaccharide mimics Fulltext Access 14 Pages 2006
Evaluation of glycolamide esters of indomethacin as potential cyclooxygenase-2 (COX-2) inhibitors Fulltext Access 14 Pages 2006
Synthesis of new class dipeptide analogues with improved permeability and antithrombotic activity Fulltext Access 14 Pages 2006
Synthesis and anticancer evaluation of bis(benzimidazoles), bis(benzoxazoles), and benzothiazoles Fulltext Access 14 Pages 2006
Structure–activity relationships and enzyme inhibition of pantothenamide-type pantothenate kinase inhibitors Fulltext Access 14 Pages 2006
Diversity-oriented chemical modification of heparin: Identification of charge-reduced N-acyl heparin derivatives having increased selectivity for heparin-binding proteins Fulltext Access 14 Pages 2006
Design, synthesis, and preliminary SAR study of 3- and 6-side-chain-extended tetrahydro-pyran analogues of cis- and trans-(6-benzhydryl-tetrahydropyran-3-yl)-benzylamine Fulltext Access 14 Pages 2006
Synthesis and biological evaluation of purine derivatives incorporating metal chelating ligands as HIV integrase inhibitors Fulltext Access 14 Pages 2006
Ligands with a 3,3-diphenylpentane skeleton for nuclear vitamin D and androgen receptors: Dual activities and metabolic activation Fulltext Access 14 Pages 2006
Synthesis and evaluation of acridine- and acridone-based anti-herpes agents with topoisomerase activity Fulltext Access 14 Pages 2006
Arylisothiocyanato selective androgen receptor modulators (SARMs) for prostate cancer Fulltext Access 14 Pages 2006
Synthesis, dihydrofolate reductase inhibition, antitumor testing, and molecular modeling study of some new 4(3H)-quinazolinone analogs Fulltext Access 14 Pages 2006
Synthesis of three classes of rhodacyanine dyes and evaluation of their in vitro and in vivo antimalarial activity Fulltext Access 14 Pages 2006
Synthesis and biological evaluation of novel pyrrolopyrrolizinones as anticancer agents Fulltext Access 14 Pages 2006
Serotype-selective, small-molecule inhibitors of the zinc endopeptidase of botulinum neurotoxin serotype A Fulltext Access 14 Pages 2006
Auditory abilities of speakers who persisted, or recovered, from stuttering Fulltext Access 14 Pages 2006
Does height modify the risk of angina associated with economic adversity? Fulltext Access 14 Pages 2006
Dengue Virus Circulation and Evolution in Mexico: A Phylogenetic Perspective Fulltext Access 14 Pages 2006
Systematic Review of the Influence of Childhood Socioeconomic Circumstances on Risk for Cardiovascular Disease in Adulthood Fulltext Access 14 Pages 2006
Endocrinopathies et dysmorphoses craniofaciales : intérêt pour I'othodontiste Fulltext Access 14 Pages 2006
Psychosocial morbidity among parents of children with congenital heart disease: A prospective longitudinal study Fulltext Access 14 Pages 2006
Nanoencapsulation I. Methods for preparation of drug-loaded polymeric nanoparticles Fulltext Access 14 Pages 2006
Novel potent and selective calcium-release-activated calcium (CRAC) channel inhibitors. Part 2: Synthesis and inhibitory activity of aryl-3-trifluoromethylpyrazoles Fulltext Access 14 Pages 2006
Quantitative structure–activity relationships for small non-peptide antagonists of CXCR2: Indirect 3D approach using the frontal polygon method Fulltext Access 14 Pages 2006
Hydrophilically enhanced 3-carboranyl thymidine analogues (3CTAs) for boron neutron capture therapy (BNCT) of cancer Fulltext Access 14 Pages 2006
Validation of the Revised 10-Item HIV Treatment Satisfaction Questionnaire Status Version and New Change Version Fulltext Access 14 Pages 2006
More belles infidèles—or why do so many bilingual studies speak with forked tongue? Fulltext Access 14 Pages 2006
Analysis of a case of the foreign accent syndrome in terms of the framework of gestural phonology Fulltext Access 14 Pages 2006
Acoustic-perceptual correlates of voice quality in elderly men and women Fulltext Access 14 Pages 2006
Auditory pattern recognition and brief tone discrimination of children with reading disorders Fulltext Access 14 Pages 2006
Optimized design and synthesis of chemical dimerizer substrates for detection of glycosynthase activity via chemical complementation Fulltext Access 14 Pages 2006
Improving the classification of multiple disorders with problem decomposition Fulltext Access 14 Pages 2006
Comparison between neural networks and multiple logistic regression to predict acute coronary syndrome in the emergency room Fulltext Access 14 Pages 2006
Indazole N-oxide derivatives as antiprotozoal agents: Synthesis, biological evaluation and mechanism of action studies Fulltext Access 14 Pages 2006
Synthesis and structure–activity studies of schweinfurthin B analogs: Evidence for the importance of a D-ring hydrogen bond donor in expression of differential cytotoxicity Fulltext Access 14 Pages 2006
Theoretical study of structure, pKa, lipophilicity, solubility, absorption, and polar surface area of some centrally acting antihypertensives Fulltext Access 14 Pages 2006
1-Benzyl-1,2,3,4-tetrahydroisoquinoline-6,7-diols as novel affinity and photoaffinity probes for β-adrenoceptor subtypes Fulltext Access 14 Pages 2006
3D QSAR study of hypolipidemic asarones by comparative molecular surface analysis Fulltext Access 14 Pages 2006
3D-QSAR studies on tripeptide aldehyde inhibitors of proteasome using CoMFA and CoMSIA methods Fulltext Access 14 Pages 2006
Polyamine conjugates of meso-tritolylporphyrin and protoporphyrin IX: Potential agents for photodynamic therapy of cancers Fulltext Access 14 Pages 2006
On the active site for hydrolysis of aryl amides and choline esters by human cholinesterases Fulltext Access 14 Pages 2006
The discovery of glycine and related amino acid-based factor Xa inhibitors Fulltext Access 14 Pages 2006
A credit-card library approach for disrupting protein–protein interactions Fulltext Access 14 Pages 2006
Solid-phase synthesis of positively charged deoxynucleic guanidine (DNG) oligonucleotide incorporating 7-deazaguanine bases Fulltext Access 14 Pages 2006
Modeling of farnesyltransferase inhibition by some thiol and non-thiol peptidomimetic inhibitors using genetic neural networks and RDF approaches Fulltext Access 14 Pages 2006
Effect of alkyl groups on the cellular hydrolysis of stavudine phosphoramidates Fulltext Access 14 Pages 2006
Design of potent inhibitors for Schistosoma japonica glutathione S-transferase Fulltext Access 15 Pages 2006
Prodrugs of 3-(3,4-dichlorobenzyloxy)-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid (MGS0039): A potent and orally active group II mGluR antagonist with antidepressant-like potential Fulltext Access 15 Pages 2006
Synthesis of functionalized biphenyl-C-nucleosides and their incorporation into oligodeoxynucleotides Fulltext Access 15 Pages 2006
Novel 1,3-dicarbonyl compounds having 2(3H)-benzazolonic heterocycles as PPARγ agonists Fulltext Access 15 Pages 2006
Flavonoids and cinnamic acid esters as inhibitors of fungal 17β-hydroxysteroid dehydrogenase: A synthesis, QSAR and modelling study Fulltext Access 15 Pages 2006
Design and synthesis of novel imidazoline derivatives with potent antihyperglycemic activity in a rat model of type 2 diabetes Fulltext Access 15 Pages 2006
Effect of functional group polarity on the antimalarial activity of spiro and dispiro-1,2,4-trioxolanes Fulltext Access 15 Pages 2006
Structural basis for androgen receptor agonists and antagonists: Interaction of SPEED 98-listed chemicals and related compounds with the androgen receptor based on an in vitro reporter gene assay and 3D-QSAR Fulltext Access 15 Pages 2006
Regiocontrolled synthesis and HIV inhibitory activity of unsymmetrical binaphthoquinone and trimeric naphthoquinone derivatives of conocurvone Fulltext Access 15 Pages 2006
C19-Steroids as androgen receptor modulators: Design, discovery, and structure-activity relationship of new steroidal androgen receptor antagonists Fulltext Access 15 Pages 2006
A new type of ketolide bearing an N-aryl-alkyl acetamide moiety at the C-9 iminoether: Synthesis and structure–activity relationships (2) Fulltext Access 15 Pages 2006
The binding of DNA intercalating and non-intercalating compounds to A-form and protonated form of poly(rC)·poly(rG): Spectroscopic and viscometric study Fulltext Access 15 Pages 2006
Consonant production patterns of young severely language-delayed children with autism Fulltext Access 15 Pages 2006
Central pattern generation and the motor infrastructure for suck, respiration, and speech Fulltext Access 15 Pages 2006
CoMFA and CoMSIA investigations of dopamine D3 receptor ligands leading to the prediction, synthesis, and evaluation of rigidized FAUC 365 analogues Fulltext Access 15 Pages 2006