Synthesis and evaluation of sphingoid analogs as inhibitors of sphingosine kinases Fulltext Access 11 Pages 2005
([2]Paracyclo[2](5,8)quinolinophan-2-yl)carbinols as catalysts for diethylzinc addition to aldehydes: cooperative effects of planar and central chirality on the asymmetric induction Fulltext Access 11 Pages 2005
Synthesis of a library of chiral α-amino acid-based borate counteranions and their application to copper catalyzed olefin cyclopropanation Fulltext Access 11 Pages 2005
Synthesis of chiral sultams and their application as chiral auxiliaries in an asymmetric Diels-Alder reaction Fulltext Access 11 Pages 2005
1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), α1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics Fulltext Access 11 Pages 2005
Molecular docking and 3D-QSAR studies on the binding mechanism of statine-based peptidomimetics with β-secretase Fulltext Access 11 Pages 2005
Novel acetylcholinesterase inhibitor as increasing agent on rhythmic bladder contractions: SAR of 8-{3-[1-(3-fluorobenzyl)piperidin-4-yl]propanoyl}-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one (TAK-802) and related compounds Fulltext Access 11 Pages 2005
Investigations of linker structure on the potency of a series of bidentate protein tyrosine phosphatase inhibitors Fulltext Access 11 Pages 2005
Cytotoxicities, cell cycle and caspase evaluations of 1,6-diaryl-3(Z)-hexen-1,5-diynes, 2-(6-aryl-3(Z)-hexen-1,5-diynyl)anilines and their derivatives Fulltext Access 11 Pages 2005
Novel anellated pyrazoloquinolin-3-ones: synthesis and in vitro BZR activity Fulltext Access 11 Pages 2005
Biphenylquinuclidines as inhibitors of squalene synthase and growth of parasitic protozoa Fulltext Access 11 Pages 2005
Synthesis of d-mannose-based azacrown ethers and their application in enantioselective reactions Fulltext Access 11 Pages 2005
Structure–activity relationships of tyrosinase inhibitory combinatorial library of 2,5-disubstituted-1,3,4-oxadiazole analogues Fulltext Access 11 Pages 2005
Design and synthesis of non-hydroxamate histone deacetylase inhibitors: identification of a selective histone acetylating agent Fulltext Access 11 Pages 2005
Exploration of a binding mode of indole amide analogues as potent histone deacetylase inhibitors and 3D-QSAR analyses Fulltext Access 11 Pages 2005
The study on the interaction between seryl-histidine dipeptide and proteins by circular dichroism and molecular modeling Fulltext Access 11 Pages 2005
Fluorinated phenylcyclopropylamines. Part 4: Effects of aryl substituents and stereochemistry on the inhibition of monoamine oxidases by 1-aryl-2-fluoro-cyclopropylamines Fulltext Access 11 Pages 2005
Synthesis, structural identification, and ligand binding of tropane ring analogs of paroxetine and an unexpected aza-bicyclo[3.2.2]nonane rearrangement product Fulltext Access 11 Pages 2005
Novel cyclosporin derivatives featuring enhanced skin penetration despite increased molecular weight Fulltext Access 11 Pages 2005
Distribution of metabolites in galled and non-galled foliar tissues of Tibouchina pulchra Fulltext Access 11 Pages 2005
Rational design of novel diketoacid-containing ferrocene inhibitors of HIV-1 integrase Fulltext Access 11 Pages 2005
Evidence for the formation of Michael adducts from reactions of (E,E)-muconaldehyde with glutathione and other thiols Fulltext Access 11 Pages 2005
Functional significance of Glu-77 and Tyr-137 within the active site of isoaspartyl dipeptidase Fulltext Access 11 Pages 2005
Effects of solvent polarity and solvent viscosity on the fluorescent properties of molecular rotors and related probes Fulltext Access 11 Pages 2005
Influence of growth phase on the essential oil composition of Hyptis suaveolens Fulltext Access 11 Pages 2005
Variation in emetine and cephaeline contents in roots of wild Ipecac (Psychotria ipecacuanha) Fulltext Access 11 Pages 2005
Exudate flavonoid aglycones of Veronica: Ecological and systematic implications Fulltext Access 11 Pages 2005
Lipophilic C-methylflavonoids with no B-ring oxygenation in Metrosideros species (Myrtaceae) Fulltext Access 11 Pages 2005
Genistein derivatives as selective estrogen receptor modulators: Sonochemical synthesis and in vivo anti-osteoporotic action Fulltext Access 11 Pages 2005
Selective sialylation of 2,3-di-O-(β-d-galactopyranosyl)-d-galactose catalyzed by Trypanosoma cruzi trans-sialidase Fulltext Access 11 Pages 2005
Palladium-catalysed C-C coupling reactions in the enantioselective synthesis of 2,4-disubstituted 4,5-dehydropiperidines using galactosylamine as a stereodifferentiating auxiliary Fulltext Access 11 Pages 2005
The design and synthesis of novel anomeric hydroperoxides: influence of the carbohydrate residue in the enantioselective epoxidation of quinones Fulltext Access 11 Pages 2005
Synthesis and characterisation of hexa- and tetrasaccharide mimics from acetobromomaltotriose and acetobromomaltose, and of C-disaccharide mimics from acetobromoglucose, obtained by electrochemical reduction on silver Fulltext Access 11 Pages 2005
Resolution of synthetically useful myo-inositol derivatives using the chiral auxiliary O-acetylmandelic acid Fulltext Access 11 Pages 2005
Immunogens from a synthetic hexasaccharide fragment of the O-SP of Vibrio cholerae O:1, serotype Ogawa Fulltext Access 11 Pages 2005
Synthesis of C-glycosyl amino acids: scope and limitations of the tandem Tebbe/Claisen approach Fulltext Access 11 Pages 2005
Diastereocontrolled multicomponent pathway to 3,4-heterocycle-annulated tetrahydro-β-carbolines Fulltext Access 11 Pages 2005
Stereoselective syntheses of pharmaceutically relevant chiral tetrahydrofurans from (S)- and (R)-glyceraldehyde derivatives Fulltext Access 11 Pages 2005
Synthesis and structure of new trichloroplatinum π-complexes: Reactivity of nitrogen lone-pair versus C–C double bond π-electrons in ligands, effect of steric hindrance Fulltext Access 11 Pages 2005
Indenols, indenones and (arylcyclohexadienyl)Mn(CO)3 π-complexes from the thermally promoted reactions of alkynes with ortho-Mn(CO)4 aryl ketone, amide, ester and aldehyde derivatives Fulltext Access 11 Pages 2005
Cyclometallation of phenylhydrazones: Synthesis, reactivity, crystal structure analysis and novel trinuclear palladium(II) cyclometallated compounds with [C, N, N′] terdentate ligands Fulltext Access 11 Pages 2005
Hydrogenation of single and multiple N–N or N–O bonds by Ru(II) catalysts in homogeneous phase Fulltext Access 11 Pages 2005
A quantum chemical study on the mechanism of S-coordinated tetrazole-thiolato formation by the reaction of organic isothiocyanates with metal azido complexes of Pt(II), Pd(II), and Sn Fulltext Access 11 Pages 2005
Synthesis, characterization and crystal structures of polymeric and dimeric triphenyltin(IV) complexes of 4-[((E)-1-{2-hydroxy-5-[(E)-2-(2-carboxyphenyl)-1-diazenyl]phenyl}methylidene)amino]aryls Fulltext Access 11 Pages 2005
Ruthenium-catalyzed reduction of racemic tricarbonyl(η6-aryl ketone)chromium complexes using transfer hydrogenation: A simple alternative to the resolution of planar chiral organometallics Fulltext Access 11 Pages 2005
Synthesis, molecular structure and catalytic activity of chiral benzamidinate nickel complexes Fulltext Access 11 Pages 2005
Chiral molecular polygons based on the Pt-alkynyl linkage: Self-assembly, characterization, and functionalization Fulltext Access 11 Pages 2005
Ruthenium–benzocrownether complexes: Synthesis, structures, catalysis and immobilisation in ionic liquids Fulltext Access 11 Pages 2005
Mononuclear ruthenium complexes containing two different phosphines in trans position: I. Synthesis and spectroscopic characterization Fulltext Access 11 Pages 2005
A comparison between the reaction of P2Ph4 with [{Co2(CO)6}2(μ-η2:μ-η2-HOCH2CCCCCH2OH)] and the reaction of [Co2(μ-PPh2)2(CO)6] with HOCH2CCCCCH2OH Fulltext Access 11 Pages 2005
Synthesis, characterization, and in vitro antimicrobial activity of organotin(IV) complexes with triazolo-pyrimidine ligands containing exocyclic oxygen atoms Fulltext Access 11 Pages 2005
New bridging ligands from methylation reactions of μ-vinyliminium diiron complexes Fulltext Access 11 Pages 2005
Bonding aspects of P-heterocyclic carbene transition metal complexes. A computational assessment Fulltext Access 11 Pages 2005
1Pyridine and phosphine functionalised N-heterocyclic carbene complexes of rhodium and iridium Fulltext Access 11 Pages 2005
Zinc N-heterocyclic carbene complexes and their polymerization of d,l-lactide Fulltext Access 11 Pages 2005
The electrochemical activity of heteroatom-stabilized Fischer-type carbene complexes Fulltext Access 11 Pages 2005
Rhodium N-heterocyclic carbene complexes: Synthesis, structure, NMR studies and catalytic activity Fulltext Access 11 Pages 2005
Asymmetric synthesis of cis-2,4-disubstituted azetidin-3-ones from metal carbene chemistry Fulltext Access 11 Pages 2005
Synthesis and structural characterisation of linear Au(I) N-heterocyclic carbene complexes: New analogues of the Au(I) phosphine drug Auranofin Fulltext Access 11 Pages 2005
Reaction of the RuTp(PR3)Cl fragment with alkynols: Formation of carbene, vinylidene, allenylidene, and carbyne complexes Fulltext Access 11 Pages 2005
New tripodal N-heterocyclic carbene chelators for small molecule activation Fulltext Access 11 Pages 2005
New potent 5-substituted benzofuroxans as inhibitors of Trypanosoma cruzi growth: Quantitative structure–activity relationship studies Fulltext Access 11 Pages 2005
Validation of a histamine H3 receptor model through structure–activity relationships for classical H3 antagonists Fulltext Access 11 Pages 2005
Binding studies and GRIND/ALMOND-based 3D QSAR analysis of benzothiazine type KATP-channel openers Fulltext Access 11 Pages 2005
Hydrophobic and electronic factors in the design of dialkylglycine decarboxylase mimics Fulltext Access 11 Pages 2005
Branched aminoglycosides: Biochemical studies and antibacterial activity of neomycin B derivatives Fulltext Access 11 Pages 2005
Synthesis and initial PET imaging of new potential dopamine D3 receptor radioligands (E)-4,3,2-[11C]methoxy-N-4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl-cinnamoylamides Fulltext Access 11 Pages 2005
Prostate cancer PET bioprobes: Synthesis of [18F]-radiolabeled hydroxyflutamide derivatives Fulltext Access 11 Pages 2005
Chiral anthracene and anthrone templates as stereocontrolling elements in Diels–Alder/retro Diels–Alder sequences Fulltext Access 11 Pages 2005
Metabolism of anthocyanins and their phenolic degradation products by the intestinal microflora Fulltext Access 11 Pages 2005
Biomimetic synthesis of acid-sensitive (−)- and (+)-caparrapi oxides, (−)- and (+)-8-epicaparrapi oxides, and (+)-dysifragin induced by artificial cyclases Fulltext Access 11 Pages 2005
Combined NMR-crystallographic and modelling investigation of the inclusion of molsidomine into α-, β- and γ-cyclodextrins Fulltext Access 11 Pages 2005
Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes Fulltext Access 11 Pages 2005
QSAR studies on 1-phenylbenzimidazoles as inhibitors of the platelet-derived growth factor Fulltext Access 11 Pages 2005
Determination of absolute configuration using vibrational circular dichroism spectroscopy: phenyl glycidic acid derivatives obtained via asymmetric epoxidation using oxone and a keto bile acid Fulltext Access 11 Pages 2005
Synthesis of enantiomerically pure cis- and trans-cyclopentane analogues of phenylalanine Fulltext Access 11 Pages 2005
Production of (R)-chiral alcohols by a hydrogen-transfer bioreduction with NADH-dependent Leifsonia alcohol dehydrogenase (LSADH) Fulltext Access 11 Pages 2005
Tin(IV) and organotin(IV) derivatives of bis(pyrazolyl)acetate: Synthesis, spectroscopic characterization and behaviour in solution.: X-ray single crystal study of bis(pyrazol-1-yl)acetatotri-iodotin(IV) [SnI3(bdmpza)] Fulltext Access 11 Pages 2005
Nickel(II) complexes bearing phosphinooxazoline ligands: Synthesis, structures and their ethylene oligomerization behaviors Fulltext Access 11 Pages 2005
Homolysis of the Ln–N bond: Synthesis, characterization and catalytic activity of organolanthanide(II) complexes with furfuryl- and tetrahydrofurfuryl-functionalized indenyl ligands Fulltext Access 11 Pages 2005
Computational study of conformations and of sulfinyl oxygen-induced pentacoordination at silicon in 4-chloro-4-silathiacyclohexane 1-oxide and 4,4-dichloro-4-silathiacyclohexane 1-oxide Fulltext Access 11 Pages 2005
Synthesis and structure of N-heterocyclic carbene complexes of rhodium and iridium derived from an imidazolium-linked cyclophane Fulltext Access 11 Pages 2005
Preparation and structural characterization of organotin(IV) complexes with ligands containing a hetero {N} atom and a hydroxy group or hydroxy and carboxyl groups Fulltext Access 11 Pages 2005