Fixation-induced cell blebbing on spread cells inversely correlates with phosphatidylinositol 4,5-bisphosphate level in the plasma membrane Fulltext Access 10 Pages 2014
The role of Cysteine 227 in subcellular localization, water permeability, and multimerization of aquaporin-11 Fulltext Access 6 Pages 2014
Differential activity of rice protein disulfide isomerase family members for disulfide bond formation and reduction Fulltext Access 5 Pages 2014
Analysis of aquaporin 9 expression in human epidermis and cultured keratinocytes Fulltext Access 6 Pages 2014
Ancestral mutations as a tool for solubilizing proteins: The case of a hydrophobic phosphate-binding protein Fulltext Access 7 Pages 2014
Identification of nuclear phosphoproteins as novel tobacco markers in mouse lung tissue following short-term exposure to tobacco smoke Fulltext Access 9 Pages 2014
Systematic analysis of transcription-level effects of neurodegenerative diseases on human brain metabolism by a newly reconstructed brain-specific metabolic network Fulltext Access 12 Pages 2014
Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2 Fulltext Access 12 Pages 2014
Molecular mechanisms in the selective basal activation of pyrabactin receptor 1: Comparative analysis of mutants Fulltext Access 14 Pages 2014
Tracing the movement of adiponectin in a parabiosis model of wild-type and adiponectin-knockout mice Fulltext Access 7 Pages 2014
Inhibitors of the Cdc34 acidic loop: A computational investigation integrating molecular dynamics, virtual screening and docking approaches Fulltext Access 12 Pages 2014
Lentiviral vector transduction of spermatozoa as a tool for the study of early development Fulltext Access 10 Pages 2014
Expression of human apolipoprotein E4 reduces insulin-receptor substrate 1 expression and Akt phosphorylation in the ageing liver Fulltext Access 6 Pages 2014
Irreversible hyperoxidation of peroxiredoxin 2 is caused by tert-butyl hydroperoxide in human red blood cells Fulltext Access 5 Pages 2014
Comprehensive enzymatic analysis of the amylolytic system in the digestive fluid of the sea hare, Aplysia kurodai: Unique properties of two α-amylases and two α-glucosidases Fulltext Access 11 Pages 2014
Ornithine cyclodeaminase/μ-crystallin homolog from the hyperthermophilic archaeon Thermococcus litoralis functions as a novel Δ1-pyrroline-2-carboxylate reductase involved in putative trans-3-hydroxy-l-proline metabolism Fulltext Access 10 Pages 2014
Cytoprotective role of the fatty acid binding protein 4 against oxidative and endoplasmic reticulum stress in 3T3-L1 adipocytes Fulltext Access 9 Pages 2014
Short-term exposure of nontumorigenic human bronchial epithelial cells to carcinogenic chromium(VI) compromises their respiratory capacity and alters their bioenergetic signature Fulltext Access 8 Pages 2014
Diminished expression of h2-calponin in prostate cancer cells promotes cell proliferation, migration and the dependence of cell adhesion on substrate stiffness Fulltext Access 10 Pages 2014
Tomato carotenoid cleavage dioxygenases 1A and 1B: Relaxed double bond specificity leads to a plenitude of dialdehydes, mono-apocarotenoids and isoprenoid volatiles Fulltext Access 10 Pages 2014
Discovery of novel interacting partners of PSMD9, a proteasomal chaperone: Role of an Atypical and versatile PDZ-domain motif interaction and identification of putative functional modules Fulltext Access 13 Pages 2014
Demethionylation of Pro-1 variants of 4-oxalocrotonate tautomerase in Escherichia coli by co-expression with an engineered methionine aminopeptidase Fulltext Access 8 Pages 2014
N-glycosylation is required for secretion and enzymatic activity of human hyaluronidase1 Fulltext Access 6 Pages 2014
Subtractive hybridization-mediated analysis of genes and in silico prediction of associated microRNAs under waterlogged conditions in sugarcane (Saccharum spp.) Fulltext Access 9 Pages 2014
Tumor suppressive miRNA-34a suppresses cell proliferation and tumor growth of glioma stem cells by targeting Akt and Wnt signaling pathways Fulltext Access 11 Pages 2014
Campylobacter jejuni gene cj0511 encodes a serine peptidase essential for colonisation Fulltext Access 5 Pages 2014
Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer Fulltext Access 10 Pages 2014
Small RNA expression and deep sequencing analyses of the nucleolus reveal the presence of nucleolus-associated microRNAs Fulltext Access 9 Pages 2014
Is there a link between proprotein convertase PC7 activity and human lipid homeostasis? Fulltext Access 5 Pages 2014
Contribution of protein phosphorylation to binding-induced folding of the SLBP–histone mRNA complex probed by phosphorus-31 NMR Fulltext Access 5 Pages 2014
An alternative allosteric regulation mechanism of an acidophilic l-lactate dehydrogenase from Enterococcus mundtii 15-1A Fulltext Access 14 Pages 2014
A new pma1 mutation identified in a chronologically long-lived fission yeast mutant Fulltext Access 5 Pages 2014
Mycobacterium tuberculosis PE25/PPE41 protein complex induces necrosis in macrophages: Role in virulence and disease reactivation? Fulltext Access 7 Pages 2014
Crystal structure of the stomatin operon partner protein from Pyrococcus horikoshii indicates the formation of a multimeric assembly Fulltext Access 9 Pages 2014
The activation mechanism of the aryl hydrocarbon receptor (AhR) by molecular chaperone HSP90 Fulltext Access 8 Pages 2014
Necrostatin-1 protects against reactive oxygen species (ROS)-induced hepatotoxicity in acetaminophen-induced acute liver failure Fulltext Access 11 Pages 2014
ROS-dependent prostate apoptosis response-4 (Par-4) up-regulation and ceramide generation are the prime signaling events associated with curcumin-induced autophagic cell death in human malignant glioma Fulltext Access 14 Pages 2014
Quercetin-3-glucoside increases low-density lipoprotein receptor (LDLR) expression, attenuates proprotein convertase subtilisin/kexin 9 (PCSK9) secretion, and stimulates LDL uptake by Huh7 human hepatocytes in culture Fulltext Access 8 Pages 2014
Conditional targeting of Ispd using paired Cas9 nickase and a single DNA template in mice Fulltext Access 6 Pages 2014
A novel peptide interferes with Mycobacterium tuberculosis virulence and survival Fulltext Access 6 Pages 2014
A dodecylamine derivative of cyanocobalamin potently inhibits the activities of cobalamin-dependent methylmalonyl-CoA mutase and methionine synthase of Caenorhabditis elegans Fulltext Access 8 Pages 2014
The respiratory chains of four strains of the alkaliphilic Bacillus clausii Fulltext Access 8 Pages 2014
mTOR inhibition increases cell viability via autophagy induction during endoplasmic reticulum stress – An experimental and modeling study Fulltext Access 10 Pages 2014
The zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylation Fulltext Access 15 Pages 2014
Nuclear export of the influenza virus ribonucleoprotein complex: Interaction of Hsc70 with viral proteins M1 and NS2 Fulltext Access 6 Pages 2014
Adenylate kinase from Streptococcus pneumoniae is essential for growth through its catalytic activity Fulltext Access 11 Pages 2014
Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP) Fulltext Access 13 Pages 2014
Changed membrane integration and catalytic site conformation are two mechanisms behind the increased Aβ42/Aβ40 ratio by presenilin 1 familial Alzheimer-linked mutations Fulltext Access 14 Pages 2014
Hammerhead ribozyme activity and oligonucleotide duplex stability in mixed solutions of water and organic compounds Fulltext Access 8 Pages 2014
Understanding the mechanism of glucose-induced relief of Rgt1-mediated repression in yeast Fulltext Access 7 Pages 2014
Survey and analysis of simple sequence repeats (SSRs) present in the genomes of plant viroids Fulltext Access 5 Pages 2014
Detection of changes in the structure and distribution map of triacylglycerol in fatty liver model by MALDI-SpiralTOF Fulltext Access 6 Pages 2014
Origin and evolution of the Peptidyl Transferase Center from proto-tRNAs Fulltext Access 4 Pages 2014
Stabilization of cyclohexanone monooxygenase by a computationally designed disulfide bond spanning only one residue Fulltext Access 7 Pages 2014
Identification of myo-inositol hexakisphosphate (IP6) as a β-secretase 1 (BACE1) inhibitory molecule in rice grain extract and digest Fulltext Access 6 Pages 2014
A novel cell-penetrating peptide derived from WT1 enhances p53 activity, induces cell senescence and displays antimelanoma activity in xeno- and syngeneic systems Fulltext Access 9 Pages 2014
The VTLISFG motif in the BH1 domain plays a significant role in regulating the degradation of Mcl-1 Fulltext Access 6 Pages 2014
DHEA supplementation in ovariectomized rats reduces impaired glucose-stimulated insulin secretion induced by a high-fat diet Fulltext Access 6 Pages 2014
Integrated mRNA and microRNA transcriptome sequencing characterizes sequence variants and mRNA–microRNA regulatory network in nasopharyngeal carcinoma model systems Fulltext Access 13 Pages 2014
The role of Importin-βs in the maintenance and lineage commitment of mouse embryonic stem cells Fulltext Access 9 Pages 2014
Similarities and differences in the biochemical and enzymological properties of the four isomaltases from Saccharomyces cerevisiae Fulltext Access 13 Pages 2014
NFκB mediates cisplatin resistance through histone modifications in head and neck squamous cell carcinoma (HNSCC) Fulltext Access 9 Pages 2014
Control of reactive oxygen species (ROS) production through histidine kinases in Aspergillus nidulans under different growth conditions Fulltext Access 6 Pages 2014
Ebselen induces reactive oxygen species (ROS)-mediated cytotoxicity in Saccharomyces cerevisiae with inhibition of glutamate dehydrogenase being a target Fulltext Access 13 Pages 2014
Functional characterization of WalRK: A two-component signal transduction system from Bacillus anthracis Fulltext Access 12 Pages 2014
Trim27-deficient mice are susceptible to streptozotocin-induced diabetes Fulltext Access 5 Pages 2014
Diphenyleneiodonium, an inhibitor of NOXes and DUOXes, is also an iodide-specific transporter Fulltext Access 5 Pages 2014
Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs Fulltext Access 12 Pages 2014
The E144 residue of Scherffelia dubia centrin discriminates between the DNA repair protein XPC and the centrosomal protein Sfi1 Fulltext Access 10 Pages 2014
Ectopic overexpression of castor bean LEAFY COTYLEDON2 (LEC2) in Arabidopsis triggers the expression of genes that encode regulators of seed maturation and oil body proteins in vegetative tissues Fulltext Access 8 Pages 2014
Up-regulation of alpha-smooth muscle actin in cardiomyocytes from non-hypertrophic and non-failing transgenic mouse hearts expressing N-terminal truncated cardiac troponin I Fulltext Access 7 Pages 2014
Aspergillus nidulans Pmts form heterodimers in all pairwise combinations Fulltext Access 7 Pages 2014
CK2 phosphorylation of human centrins 1 and 2 regulates their binding to the DNA repair protein XPC, the centrosomal protein Sfi1 and the phototransduction protein transducin β Fulltext Access 13 Pages 2014
The ALS/FTLD-related RNA-binding proteins TDP-43 and FUS have common downstream RNA targets in cortical neurons Fulltext Access 10 Pages 2014
EF-hand motifs of diacylglycerol kinase α interact intra-molecularly with its C1 domains Fulltext Access 6 Pages 2014
Fructose 1-phosphate is the one and only physiological effector of the Cra (FruR) regulator of Pseudomonas putida Fulltext Access 10 Pages 2014
CD9 may contribute to the survival of human germinal center B cells by facilitating the interaction with follicular dendritic cells Fulltext Access 7 Pages 2014
Interaction of Sesbania mosaic virus (SeMV) RNA-dependent RNA polymerase (RdRp) with the p10 domain of polyprotein 2a and its implications in SeMV replication Fulltext Access 8 Pages 2014
Staphylococcal nuclease domain containing-1 (SND1) promotes migration and invasion via angiotensin II type 1 receptor (AT1R) and TGFβ signaling Fulltext Access 9 Pages 2014
The effects of the heme precursor 5-aminolevulinic acid (ALA) on REV-ERBα activation Fulltext Access 6 Pages 2014
Establishment of a mast cell line, NCL-2, without Kit mutation, derived from NC mouse bone marrow Fulltext Access 5 Pages 2014
Biophysical analysis of the interaction of the serum protein human β2GPI with bacterial lipopolysaccharide Fulltext Access 9 Pages 2014
Inhibition of malignant phenotypes of human osteosarcoma cells by a gene silencer, a pyrrole–imidazole polyamide, which targets an E-box motif Fulltext Access 7 Pages 2014
Mutation G805R in the transmembrane domain of the LDL receptor gene causes familial hypercholesterolemia by inducing ectodomain cleavage of the LDL receptor in the endoplasmic reticulum Fulltext Access 7 Pages 2014
A word of caution about biological inference – Revisiting cysteine covalent state predictions Fulltext Access 5 Pages 2014
The role of autophagy in the intracellular survival of Campylobacter concisus Fulltext Access 9 Pages 2014
Functional characterization of diverse ring-hydroxylating oxygenases and induction of complex aromatic catabolic gene clusters in Sphingobium sp. PNB Fulltext Access 11 Pages 2014
Structure of the C-terminal domain of AspA (antigen I/II-family) protein from Streptococcus pyogenes Fulltext Access 7 Pages 2014
The DNA intercalators ethidium bromide and propidium iodide also bind to core histones Fulltext Access 9 Pages 2014
Identification and characterization of trans-3-hydroxy-l-proline dehydratase and Δ1-pyrroline-2-carboxylate reductase involved in trans-3-hydroxy-l-proline metabolism of bacteria Fulltext Access 11 Pages 2014
Mutational and crystallographic analysis of l-amino acid oxidase/monooxygenase from Pseudomonas sp. AIU 813: Interconversion between oxidase and monooxygenase activities Fulltext Access 9 Pages 2014
Analysis of essential pathways for self-renewal in common marmoset embryonic stem cells Fulltext Access 7 Pages 2014