European Journal of Pharmacology - Volume 759 

ReviewReverse translation of failed treatments can help improving the validity of preclinical animal models

Fulltext Access 5 Pages 2015

The transferability from rat subacute 4-week oral toxicity study to translational research exemplified by two pharmaceutical immunosuppressants and two environmental pollutants with immunomodulating properties

Fulltext Access 17 Pages 2015

The utility of animal models in developing immunosuppressive agents

Fulltext Access 8 Pages 2015

ReviewAnimal models of rheumatoid arthritis: How informative are they?

Fulltext Access 9 Pages 2015

Translational value of animal models of asthma: Challenges and promises

Fulltext Access 6 Pages 2015

Preclinical murine models of Chronic Obstructive Pulmonary Disease

Fulltext Access 7 Pages 2015

Experimental colitis models: Insights into the pathogenesis of inflammatory bowel disease and translational issues

Fulltext Access 12 Pages 2015

Considerations on pig models for appetite, metabolic syndrome and obese type 2 diabetes: From food intake to metabolic disease

Fulltext Access 9 Pages 2015

Validity of animal models of type 1 diabetes, and strategies to enhance their utility in translational research

Fulltext Access 10 Pages 2015

Translational value of animal models of kidney failure

Fulltext Access 16 Pages 2015

Cardiovascular pharmacotherapy: Innovation stuck in translation

Fulltext Access 5 Pages 2015

Animal models of Multiple Sclerosis

Fulltext Access 10 Pages 2015

Neurobiological studies of chronic pain and analgesia: Rationale and refinements

Fulltext Access 13 Pages 2015

ReviewInvestigating the mechanism(s) underlying switching between states in bipolar disorder

Fulltext Access 12 Pages 2015

ReviewSwitching to zebrafish neurobehavioral models: The obsessive-compulsive disorder paradigm

Fulltext Access 9 Pages 2015

From neural to genetic substrates of panic disorder: Insights from human and mouse studies

Fulltext Access 15 Pages 2015

The safety, efficacy and regulatory triangle in drug development: Impact for animal models and the use of animals

Fulltext Access 11 Pages 2015

Mouse models rarely mimic the transcriptome of human neurodegenerative diseases: A systematic bioinformatics-based critique of preclinical models

Fulltext Access 17 Pages 2015

Rodent models for human diseases

Fulltext Access 6 Pages 2015

ReviewThe translational value of non-human primates in preclinical research on infection and immunopathology

Fulltext Access 15 Pages 2015

Estimating vaccine efficacy using animal efficacy data

Fulltext Access 6 Pages 2015

Regulatory acceptance of animal models of disease to support clinical trials of medicines and advanced therapy medicinal products

Fulltext Access 12 Pages 2015

Ethological concepts enhance the translational value of animal models

Fulltext Access 9 Pages 2015

Back to the future of psychopharmacology: A perspective on animal models in drug discovery

Fulltext Access 34 Pages 2015

Integrated analysis of toxicity data of two pharmaceutical immunosuppressants and two environmental pollutants with immunomodulating properties to improve the understanding of side effects-A toxicopathologist׳s view

Fulltext Access 13 Pages 2015

ReviewGeneration of improved mouse models for the study of hepatitis C virus

Fulltext Access 13 Pages 2015

Paving the path to HIV neurotherapy: Predicting SIV CNS disease

Fulltext Access 10 Pages 2015

The multifactorial role of the 3Rs in shifting the harm-benefit analysis in animal models of disease

Fulltext Access 11 Pages 2015

ReviewAnimal models for osteoporosis

Fulltext Access 8 Pages 2015

ReviewFrom mice to mind: Strategies and progress in translating neuroregeneration

Fulltext Access 11 Pages 2015

Carpentier-Edwards aortic pericardial bioprosthetic valve as a valid control in preclinical in vivo ovine studies

Fulltext Access 8 Pages 2015

Translational research for Parkinson׳s disease: The value of pre-clinical primate models

Fulltext Access 9 Pages 2015

The use of EEG parameters as predictors of drug effects on cognition

Fulltext Access 6 Pages 2015